Protective Role of microRNA-31 in Acetaminophen-Induced Liver Injury: A Negative Regulator of c-Jun N-Terminal Kinase (JNK) Signaling PathwaySummary
Background & Aims: Sustained c-Jun N-terminal kinase (JNK) activation plays a major role in drug-induced liver injury (DILI). Stress-responsive microRNA-31 (miR-31) has been implicated in regulating different cellular damage, and JNK activation could induce miR-31 expression. However, the re...
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Autores principales: | Jianxin Zheng, Hong Zhou, Taihua Yang, Jinchuan Liu, Tian Qin, Xiangqian Gu, Ji Wu, Yi Zhang, Honglin Wang, Yuanjia Tang, Feng Xue, Yimin Mao, Qiang Xia |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/beabaa901cb04e698d21b5567b0393e5 |
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