A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports

Multisystem inflammatory syndrome in children is a newly described condition temporarily associated with severe acute respiratory syndrome coronavirus 2. The primary observations indicated coronavirus disease 2019 infection in children to be mild. However, recent reports have revealed a correlation...

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Autores principales:	Agnieszka Poniecka, Elżbieta Smolewska
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2021
Materias:	paediatric multisystem inflammatory syndrome sars-cov-2 infection secondary haemophagocytic lymphohistiocytosis macrophage activation syndrome. Medicine R
Acceso en línea:	https://doaj.org/article/beaf766e0d884c32839a66f37c38738a
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spelling	oai:doaj.org-article:beaf766e0d884c32839a66f37c38738a2021-12-02T19:19:13ZA fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports0034-62332084-983410.5114/reum.2021.102871https://doaj.org/article/beaf766e0d884c32839a66f37c38738a2021-02-01T00:00:00Zhttps://www.termedia.pl/A-fine-line-between-macrophage-activation-syndrome-and-multisystem-inflammatory-syndrome-in-children-literature-review-based-on-two-case-reports,18,43087,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Multisystem inflammatory syndrome in children is a newly described condition temporarily associated with severe acute respiratory syndrome coronavirus 2. The primary observations indicated coronavirus disease 2019 infection in children to be mild. However, recent reports have revealed a correlation between multisystem inflammatory symptoms and coronavirus infection. The manifestation of the disease is similar to Kawasaki disease, toxic shock syndrome and macrophage activation syndrome. Treatment includes intravenous corticosteroids, immunoglobulin and biological therapy (anakinra, tocilizumab, infliximab). In this article we compare world reports of multisystem inflammatory syndrome in children to case reports of two patients who were hospitalized recently at the Department of Paediatric Cardiology and Rheumatology. In the course of diagnostics they presented numerous symptoms which required differentiation from multisystem inflammatory syndrome in children.Agnieszka PonieckaElżbieta SmolewskaTermedia Publishing Housearticlepaediatric multisystem inflammatory syndrome sars-cov-2 infection secondary haemophagocytic lymphohistiocytosis macrophage activation syndrome.MedicineRENRheumatology, Vol 59, Iss 1, Pp 47-57 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	paediatric multisystem inflammatory syndrome sars-cov-2 infection secondary haemophagocytic lymphohistiocytosis macrophage activation syndrome. Medicine R
spellingShingle	paediatric multisystem inflammatory syndrome sars-cov-2 infection secondary haemophagocytic lymphohistiocytosis macrophage activation syndrome. Medicine R Agnieszka Poniecka Elżbieta Smolewska A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
description	Multisystem inflammatory syndrome in children is a newly described condition temporarily associated with severe acute respiratory syndrome coronavirus 2. The primary observations indicated coronavirus disease 2019 infection in children to be mild. However, recent reports have revealed a correlation between multisystem inflammatory symptoms and coronavirus infection. The manifestation of the disease is similar to Kawasaki disease, toxic shock syndrome and macrophage activation syndrome. Treatment includes intravenous corticosteroids, immunoglobulin and biological therapy (anakinra, tocilizumab, infliximab). In this article we compare world reports of multisystem inflammatory syndrome in children to case reports of two patients who were hospitalized recently at the Department of Paediatric Cardiology and Rheumatology. In the course of diagnostics they presented numerous symptoms which required differentiation from multisystem inflammatory syndrome in children.
format	article
author	Agnieszka Poniecka Elżbieta Smolewska
author_facet	Agnieszka Poniecka Elżbieta Smolewska
author_sort	Agnieszka Poniecka
title	A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
title_short	A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
title_full	A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
title_fullStr	A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
title_full_unstemmed	A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
title_sort	a fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports
publisher	Termedia Publishing House
publishDate	2021
url	https://doaj.org/article/beaf766e0d884c32839a66f37c38738a
work_keys_str_mv	AT agnieszkaponiecka afinelinebetweenmacrophageactivationsyndromeandmultisysteminflammatorysyndromeinchildrenliteraturereviewbasedontwocasereports AT elzbietasmolewska afinelinebetweenmacrophageactivationsyndromeandmultisysteminflammatorysyndromeinchildrenliteraturereviewbasedontwocasereports
_version_	1718376875617681408

A fine line between macrophage activation syndrome and multisystem inflammatory syndrome in children – literature review based on two case reports

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