Review: management of Parkinson's disease
David J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage...
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Dove Medical Press
2013
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oai:doaj.org-article:beb2e00110a74aba85616cdda12e86062021-12-02T06:51:45ZReview: management of Parkinson's disease1176-63281178-2021https://doaj.org/article/beb2e00110a74aba85616cdda12e86062013-03-01T00:00:00Zhttp://www.dovepress.com/review-management-of-parkinson39s-disease-a12353https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021David J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment options makes the disease management often complicated even when the presence of PD seems undoubted. In addition, nonmotor symptoms and side effects of some therapies constitute some pitfalls already in the preclinical state or at the beginnings of the disease, especially with the progressive effect on patients. Therefore, this review aimed to summarize study results and depict recommended medical treatments for the most common motor and nonmotor symptoms in PD. Additionally, emerging new therapeutic options such as continuous pump therapies, eg, with apomorphine or parenteral levodopa, or the implantation of electrodes for deep brain stimulation were also considered. Keywords: Parkinson's disease, disease management, side effects, nonmotor symptoms, DBS, pump therapiesPedrosa DJTimmermann LDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 321-340 (2013) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Pedrosa DJ Timmermann L Review: management of Parkinson's disease |
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David J Pedrosa, Lars Timmermann Department of Neurology, University Hospital Cologne, Cologne, Germany Abstract: Parkinson's disease (PD) is one of the most frequent neurological diseases. Despite the modern imaging and nuclear techniques which help to diagnose it in a very early stage and lead to a better discrimination of similar diseases, PD has remained a clinical diagnosis. The increasing number of available treatment options makes the disease management often complicated even when the presence of PD seems undoubted. In addition, nonmotor symptoms and side effects of some therapies constitute some pitfalls already in the preclinical state or at the beginnings of the disease, especially with the progressive effect on patients. Therefore, this review aimed to summarize study results and depict recommended medical treatments for the most common motor and nonmotor symptoms in PD. Additionally, emerging new therapeutic options such as continuous pump therapies, eg, with apomorphine or parenteral levodopa, or the implantation of electrodes for deep brain stimulation were also considered. Keywords: Parkinson's disease, disease management, side effects, nonmotor symptoms, DBS, pump therapies |
format |
article |
author |
Pedrosa DJ Timmermann L |
author_facet |
Pedrosa DJ Timmermann L |
author_sort |
Pedrosa DJ |
title |
Review: management of Parkinson's disease |
title_short |
Review: management of Parkinson's disease |
title_full |
Review: management of Parkinson's disease |
title_fullStr |
Review: management of Parkinson's disease |
title_full_unstemmed |
Review: management of Parkinson's disease |
title_sort |
review: management of parkinson's disease |
publisher |
Dove Medical Press |
publishDate |
2013 |
url |
https://doaj.org/article/beb2e00110a74aba85616cdda12e8606 |
work_keys_str_mv |
AT pedrosadj reviewmanagementofparkinsonamp39sdisease AT timmermannl reviewmanagementofparkinsonamp39sdisease |
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