An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

Human polymorphisms in nicotinic acetylcholine receptor genes have been linked to both smoking and lung diseases like Chronic Obstructive Pulmonary Disease (COPD) or lung cancer. Here the authors identify a direct role for a human coding polymorphism in COPD-like lesions independent of smoke or nico...

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Autores principales: Julie Routhier, Stéphanie Pons, Mohamed Lamine Freidja, Véronique Dalstein, Jérôme Cutrona, Antoine Jonquet, Nathalie Lalun, Jean-Claude Mérol, Mark Lathrop, Jerry A. Stitzel, Gwenola Kervoaze, Muriel Pichavant, Philippe Gosset, Jean-Marie Tournier, Philippe Birembaut, Valérian Dormoy, Uwe Maskos
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/beb4aa7e77234ba9bf33270113914c9a
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