Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells

Understanding the interaction of nanomaterials and immune cells at the biomolecular level is of great significance in therapeutic applications. Here, the authors investigated the interaction of graphene oxide nanomaterials and several immune cell subpopulations using single-cell mass cytometry and...

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Autores principales: Marco Orecchioni, Davide Bedognetti, Leon Newman, Claudia Fuoco, Filomena Spada, Wouter Hendrickx, Francesco M. Marincola, Francesco Sgarrella, Artur Filipe Rodrigues, Cécilia Ménard-Moyon, Gianni Cesareni, Kostas Kostarelos, Alberto Bianco, Lucia G Delogu
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/beb5f497aec64fa9b9b42ae008175241
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spelling oai:doaj.org-article:beb5f497aec64fa9b9b42ae0081752412021-12-02T17:01:18ZSingle-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells10.1038/s41467-017-01015-32041-1723https://doaj.org/article/beb5f497aec64fa9b9b42ae0081752412017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01015-3https://doaj.org/toc/2041-1723Understanding the interaction of nanomaterials and immune cells at the biomolecular level is of great significance in therapeutic applications. Here, the authors investigated the interaction of graphene oxide nanomaterials and several immune cell subpopulations using single-cell mass cytometry and genome-wide transcriptome analysis.Marco OrecchioniDavide BedognettiLeon NewmanClaudia FuocoFilomena SpadaWouter HendrickxFrancesco M. MarincolaFrancesco SgarrellaArtur Filipe RodriguesCécilia Ménard-MoyonGianni CesareniKostas KostarelosAlberto BiancoLucia G DeloguNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marco Orecchioni
Davide Bedognetti
Leon Newman
Claudia Fuoco
Filomena Spada
Wouter Hendrickx
Francesco M. Marincola
Francesco Sgarrella
Artur Filipe Rodrigues
Cécilia Ménard-Moyon
Gianni Cesareni
Kostas Kostarelos
Alberto Bianco
Lucia G Delogu
Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
description Understanding the interaction of nanomaterials and immune cells at the biomolecular level is of great significance in therapeutic applications. Here, the authors investigated the interaction of graphene oxide nanomaterials and several immune cell subpopulations using single-cell mass cytometry and genome-wide transcriptome analysis.
format article
author Marco Orecchioni
Davide Bedognetti
Leon Newman
Claudia Fuoco
Filomena Spada
Wouter Hendrickx
Francesco M. Marincola
Francesco Sgarrella
Artur Filipe Rodrigues
Cécilia Ménard-Moyon
Gianni Cesareni
Kostas Kostarelos
Alberto Bianco
Lucia G Delogu
author_facet Marco Orecchioni
Davide Bedognetti
Leon Newman
Claudia Fuoco
Filomena Spada
Wouter Hendrickx
Francesco M. Marincola
Francesco Sgarrella
Artur Filipe Rodrigues
Cécilia Ménard-Moyon
Gianni Cesareni
Kostas Kostarelos
Alberto Bianco
Lucia G Delogu
author_sort Marco Orecchioni
title Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
title_short Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
title_full Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
title_fullStr Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
title_full_unstemmed Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
title_sort single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/beb5f497aec64fa9b9b42ae008175241
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