Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses.
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever. Amapari (AMAV) and Tacaribe (TCRV), two nonpathogenic NW clade B arenaviruses that do not use human TfR1, are closely related t...
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Autores principales: | Jonathan Abraham, Jo Ann Kwong, César G Albariño, Jiajie G Lu, Sheli R Radoshitzky, Jorge Salazar-Bravo, Michael Farzan, Christina F Spiropoulou, Hyeryun Choe |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/beb879c296f74e959df4baba2bec631c |
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