C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

In breast cancer TGF-β regulates C/EBPα and can induce epithelial-to-mesenchymal transition (EMT). Here, the authors show that C/EBPα maintains epithelial homeostasis and prevents EMT-mediated tumorigenesis.

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Detalles Bibliográficos
Autores principales: Ana Rita Lourenço, M. Guy Roukens, Danielle Seinstra, Cynthia L. Frederiks, Cornelieke E. Pals, Stephin J. Vervoort, Andreia S. Margarido, Jacco van Rheenen, Paul J. Coffer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/beb8ddfc0b0b4b249f1fbb7841a7699b
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