The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study

Eyob Alemayehu Gebreyohannes,1 Akshaya Srikanth Bhagavathula,1,2 Tadesse Melaku Abegaz,1 Tamrat Befekadu Abebe,1 Sewunet Admasu Belachew,1 Henok Getachew Tegegn,1 Sarab M Mansoor3 1Department of Clinical Pharmacy, School of Pharmacy, University of Gondar-College of Medicine and Health Sciences, Gond...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gebreyohannes EA, Bhagavathula AS, Abegaz TM, Abebe TB, Belachew SA, Tegegn HG, Mansoor SM
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2019
Materias:
HIV
ADR
Acceso en línea:https://doaj.org/article/bebd838525e643cdb1b88f2b41261f61
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:bebd838525e643cdb1b88f2b41261f61
record_format dspace
spelling oai:doaj.org-article:bebd838525e643cdb1b88f2b41261f612021-12-02T04:47:16ZThe effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study1179-1373https://doaj.org/article/bebd838525e643cdb1b88f2b41261f612019-01-01T00:00:00Zhttps://www.dovepress.com/the-effectiveness-of-pictogram-intervention-in-the-identification-and--peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Eyob Alemayehu Gebreyohannes,1 Akshaya Srikanth Bhagavathula,1,2 Tadesse Melaku Abegaz,1 Tamrat Befekadu Abebe,1 Sewunet Admasu Belachew,1 Henok Getachew Tegegn,1 Sarab M Mansoor3 1Department of Clinical Pharmacy, School of Pharmacy, University of Gondar-College of Medicine and Health Sciences, Gondar, Ethiopia; 2Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates; 3School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, NSW, Australia Purpose: In health communication, pictogram has a comprehensive place to aid attention, memory recall, and promote adherence. This study was conducted to assess whether pictorial intervention would help to identify and improve adverse drug reactions (ADRs) reporting in an antiretroviral therapy (ART) clinic in Northwest Ethiopia.Patients and methods: A cross-sectional study on ART-naïve HIV-positive patients was conducted from July 2015 to January 2016. The patients were randomly categorized into two groups. Group A was subjected to receive pictorial medication information and a pictogram-enhanced tool to identify and report ADRs, while group B did not receive any pictogram-enhanced tool.Results: A total of 207 ART-naïve HIV-positive patients who were registered for the ART treatment attending Gondar University Hospital ART clinic were included. Bivariate analysis showed that sociodemographic characteristics, such as age, sex, education, employment, and marital status were the main predictors of identifying and reporting ADRs. Males were twice more likely to identify ADRs than females. Univariate analysis revealed that patients assigned to group A showed a significant association with the ability to identify ART medications using pictograms. Patients assigned to group A were more likely to identify lamivudine (OR [95% CI] =7.536 [4.042–14.021], P≤0.001), tenofovir (OR [95% CI] =6.250 [2.855–13.682], P≤0.001), nevirapine (OR [95% CI] =5.320 [1.954–14.484], P=0.001), efavirenz (OR [95% CI] =3.929 [1.876–8.228], P≤0.001), and zidovudine (OR [95% CI] =3.570 [1.602–7.960], P=0.002) using pictograms. Patients in group A were 4.3 times more likely to identify diarrhea as an ADR using pictogram compared with group B.Conclusion: The use of pictorial representation resulted in only slight improvement in identification and reporting of ADRs among naïve HIV-positive patients with limited literacy in Northwest Ethiopia. This representation of ADRs merits further investigation with regard to ADR identification and promoting patients’ safety, particularly for HIV-positive patients with limited educational levels. Keywords: HIV, AIDS, ADR, pictogram, Gondar, Ethiopia, HAARTGebreyohannes EABhagavathula ASAbegaz TMAbebe TBBelachew SATegegn HGMansoor SMDove Medical PressarticleHIVAIDSADRPictogramGondarEthiopiaImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 11, Pp 9-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic HIV
AIDS
ADR
Pictogram
Gondar
Ethiopia
Immunologic diseases. Allergy
RC581-607
spellingShingle HIV
AIDS
ADR
Pictogram
Gondar
Ethiopia
Immunologic diseases. Allergy
RC581-607
Gebreyohannes EA
Bhagavathula AS
Abegaz TM
Abebe TB
Belachew SA
Tegegn HG
Mansoor SM
The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
description Eyob Alemayehu Gebreyohannes,1 Akshaya Srikanth Bhagavathula,1,2 Tadesse Melaku Abegaz,1 Tamrat Befekadu Abebe,1 Sewunet Admasu Belachew,1 Henok Getachew Tegegn,1 Sarab M Mansoor3 1Department of Clinical Pharmacy, School of Pharmacy, University of Gondar-College of Medicine and Health Sciences, Gondar, Ethiopia; 2Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates; 3School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, NSW, Australia Purpose: In health communication, pictogram has a comprehensive place to aid attention, memory recall, and promote adherence. This study was conducted to assess whether pictorial intervention would help to identify and improve adverse drug reactions (ADRs) reporting in an antiretroviral therapy (ART) clinic in Northwest Ethiopia.Patients and methods: A cross-sectional study on ART-naïve HIV-positive patients was conducted from July 2015 to January 2016. The patients were randomly categorized into two groups. Group A was subjected to receive pictorial medication information and a pictogram-enhanced tool to identify and report ADRs, while group B did not receive any pictogram-enhanced tool.Results: A total of 207 ART-naïve HIV-positive patients who were registered for the ART treatment attending Gondar University Hospital ART clinic were included. Bivariate analysis showed that sociodemographic characteristics, such as age, sex, education, employment, and marital status were the main predictors of identifying and reporting ADRs. Males were twice more likely to identify ADRs than females. Univariate analysis revealed that patients assigned to group A showed a significant association with the ability to identify ART medications using pictograms. Patients assigned to group A were more likely to identify lamivudine (OR [95% CI] =7.536 [4.042–14.021], P≤0.001), tenofovir (OR [95% CI] =6.250 [2.855–13.682], P≤0.001), nevirapine (OR [95% CI] =5.320 [1.954–14.484], P=0.001), efavirenz (OR [95% CI] =3.929 [1.876–8.228], P≤0.001), and zidovudine (OR [95% CI] =3.570 [1.602–7.960], P=0.002) using pictograms. Patients in group A were 4.3 times more likely to identify diarrhea as an ADR using pictogram compared with group B.Conclusion: The use of pictorial representation resulted in only slight improvement in identification and reporting of ADRs among naïve HIV-positive patients with limited literacy in Northwest Ethiopia. This representation of ADRs merits further investigation with regard to ADR identification and promoting patients’ safety, particularly for HIV-positive patients with limited educational levels. Keywords: HIV, AIDS, ADR, pictogram, Gondar, Ethiopia, HAART
format article
author Gebreyohannes EA
Bhagavathula AS
Abegaz TM
Abebe TB
Belachew SA
Tegegn HG
Mansoor SM
author_facet Gebreyohannes EA
Bhagavathula AS
Abegaz TM
Abebe TB
Belachew SA
Tegegn HG
Mansoor SM
author_sort Gebreyohannes EA
title The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
title_short The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
title_full The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
title_fullStr The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
title_full_unstemmed The effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve HIV patients in Ethiopia: a cross-sectional study
title_sort effectiveness of pictogram intervention in the identification and reporting of adverse drug reactions in naïve hiv patients in ethiopia: a cross-sectional study
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/bebd838525e643cdb1b88f2b41261f61
work_keys_str_mv AT gebreyohannesea theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT bhagavathulaas theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT abegaztm theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT abebetb theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT belachewsa theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT tegegnhg theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT mansoorsm theeffectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT gebreyohannesea effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT bhagavathulaas effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT abegaztm effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT abebetb effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT belachewsa effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT tegegnhg effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
AT mansoorsm effectivenessofpictograminterventionintheidentificationandreportingofadversedrugreactionsinnaiumlvehivpatientsinethiopiaacrosssectionalstudy
_version_ 1718401032922333184