Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.

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Autores principales:	Martin Pauli, Mila M. Paul, Sven Proppert, Achmed Mrestani, Marzieh Sharifi, Felix Repp, Lydia Kürzinger, Philip Kollmannsberger, Markus Sauer, Manfred Heckmann, Anna-Leena Sirén
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/bec0604fa81c4f76811712b1600e858c
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spelling	oai:doaj.org-article:bec0604fa81c4f76811712b1600e858c2021-12-02T11:44:59ZTargeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections10.1038/s42003-021-01939-z2399-3642https://doaj.org/article/bec0604fa81c4f76811712b1600e858c2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01939-zhttps://doaj.org/toc/2399-3642Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.Martin PauliMila M. PaulSven ProppertAchmed MrestaniMarzieh SharifiFelix ReppLydia KürzingerPhilip KollmannsbergerMarkus SauerManfred HeckmannAnna-Leena SirénNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Martin Pauli Mila M. Paul Sven Proppert Achmed Mrestani Marzieh Sharifi Felix Repp Lydia Kürzinger Philip Kollmannsberger Markus Sauer Manfred Heckmann Anna-Leena Sirén Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
description	Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.
format	article
author	Martin Pauli Mila M. Paul Sven Proppert Achmed Mrestani Marzieh Sharifi Felix Repp Lydia Kürzinger Philip Kollmannsberger Markus Sauer Manfred Heckmann Anna-Leena Sirén
author_facet	Martin Pauli Mila M. Paul Sven Proppert Achmed Mrestani Marzieh Sharifi Felix Repp Lydia Kürzinger Philip Kollmannsberger Markus Sauer Manfred Heckmann Anna-Leena Sirén
author_sort	Martin Pauli
title	Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
title_short	Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
title_full	Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
title_fullStr	Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
title_full_unstemmed	Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
title_sort	targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bec0604fa81c4f76811712b1600e858c
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Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

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