On chaotic dynamics in transcription factors and the associated effects in differential gene regulation

It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene expression and can generate phenotypic heterogeneity....

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Autores principales:	Mathias L. Heltberg, Sandeep Krishna, Mogens H. Jensen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bec13c5bbbb440a98ed977675cd73994
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id	oai:doaj.org-article:bec13c5bbbb440a98ed977675cd73994
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spelling	oai:doaj.org-article:bec13c5bbbb440a98ed977675cd739942021-12-02T14:39:19ZOn chaotic dynamics in transcription factors and the associated effects in differential gene regulation10.1038/s41467-018-07932-12041-1723https://doaj.org/article/bec13c5bbbb440a98ed977675cd739942019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07932-1https://doaj.org/toc/2041-1723It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene expression and can generate phenotypic heterogeneity.Mathias L. HeltbergSandeep KrishnaMogens H. JensenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mathias L. Heltberg Sandeep Krishna Mogens H. Jensen On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
description	It is becoming clear that the dynamics of transcription factors may be important for gene regulation. Here, the authors study the implications of oscillatory and chaotic dynamics of NF-κB and demonstrate that it allows a degree of control of gene expression and can generate phenotypic heterogeneity.
format	article
author	Mathias L. Heltberg Sandeep Krishna Mogens H. Jensen
author_facet	Mathias L. Heltberg Sandeep Krishna Mogens H. Jensen
author_sort	Mathias L. Heltberg
title	On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
title_short	On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
title_full	On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
title_fullStr	On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
title_full_unstemmed	On chaotic dynamics in transcription factors and the associated effects in differential gene regulation
title_sort	on chaotic dynamics in transcription factors and the associated effects in differential gene regulation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bec13c5bbbb440a98ed977675cd73994
work_keys_str_mv	AT mathiaslheltberg onchaoticdynamicsintranscriptionfactorsandtheassociatedeffectsindifferentialgeneregulation AT sandeepkrishna onchaoticdynamicsintranscriptionfactorsandtheassociatedeffectsindifferentialgeneregulation AT mogenshjensen onchaoticdynamicsintranscriptionfactorsandtheassociatedeffectsindifferentialgeneregulation
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On chaotic dynamics in transcription factors and the associated effects in differential gene regulation

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