MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such changes are unknown. Here, we address this issue from a developmental perspective, by analyzing mRNA and microRNA (miRNA) expression in two brain regions withi...

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Auteurs principaux: Mehmet Somel, Xiling Liu, Lin Tang, Zheng Yan, Haiyang Hu, Song Guo, Xi Jiang, Xiaoyu Zhang, Guohua Xu, Gangcai Xie, Na Li, Yuhui Hu, Wei Chen, Svante Pääbo, Philipp Khaitovich
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/beca1738ead747b09d1e1f61df0aae29
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