MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

Molecular analysis of archival formalin-fixed clinical tissues can be difficult. Here, researchers have developed MethCORR, an approach that infers gene expression from DNA methylation data and use the approach for molecular characterization and prognostication of colorectal cancer using archival sa...

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Autores principales:	Trine B. Mattesen, Mads H. Rasmussen, Juan Sandoval, Halit Ongen, Sigrid S. Árnadóttir, Josephine Gladov, Anna Martinez-Cardus, Manuel Castro de Moura, Anders H. Madsen, Søren Laurberg, Emmanouil T. Dermitzakis, Manel Esteller, Claus L. Andersen, Jesper B. Bramsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/becb7cbc91e549f599c082728cbc7bdb
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spelling	oai:doaj.org-article:becb7cbc91e549f599c082728cbc7bdb2021-12-02T17:32:12ZMethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer10.1038/s41467-020-16000-62041-1723https://doaj.org/article/becb7cbc91e549f599c082728cbc7bdb2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16000-6https://doaj.org/toc/2041-1723Molecular analysis of archival formalin-fixed clinical tissues can be difficult. Here, researchers have developed MethCORR, an approach that infers gene expression from DNA methylation data and use the approach for molecular characterization and prognostication of colorectal cancer using archival samples.Trine B. MattesenMads H. RasmussenJuan SandovalHalit OngenSigrid S. ÁrnadóttirJosephine GladovAnna Martinez-CardusManuel Castro de MouraAnders H. MadsenSøren LaurbergEmmanouil T. DermitzakisManel EstellerClaus L. AndersenJesper B. BramsenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Trine B. Mattesen Mads H. Rasmussen Juan Sandoval Halit Ongen Sigrid S. Árnadóttir Josephine Gladov Anna Martinez-Cardus Manuel Castro de Moura Anders H. Madsen Søren Laurberg Emmanouil T. Dermitzakis Manel Esteller Claus L. Andersen Jesper B. Bramsen MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
description	Molecular analysis of archival formalin-fixed clinical tissues can be difficult. Here, researchers have developed MethCORR, an approach that infers gene expression from DNA methylation data and use the approach for molecular characterization and prognostication of colorectal cancer using archival samples.
format	article
author	Trine B. Mattesen Mads H. Rasmussen Juan Sandoval Halit Ongen Sigrid S. Árnadóttir Josephine Gladov Anna Martinez-Cardus Manuel Castro de Moura Anders H. Madsen Søren Laurberg Emmanouil T. Dermitzakis Manel Esteller Claus L. Andersen Jesper B. Bramsen
author_facet	Trine B. Mattesen Mads H. Rasmussen Juan Sandoval Halit Ongen Sigrid S. Árnadóttir Josephine Gladov Anna Martinez-Cardus Manuel Castro de Moura Anders H. Madsen Søren Laurberg Emmanouil T. Dermitzakis Manel Esteller Claus L. Andersen Jesper B. Bramsen
author_sort	Trine B. Mattesen
title	MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
title_short	MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
title_full	MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
title_fullStr	MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
title_full_unstemmed	MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
title_sort	methcorr modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/becb7cbc91e549f599c082728cbc7bdb
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MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

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