Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity

Aldehyde-alcohol dehydrogenase (AdhE) converts acetyl-CoA to ethanol and plays an important role in bacterial fermentation. Here the authors present the 3.5 Å cryo-EM structure of full-length E. coli AdhE, which reveals a right-handed helical spirosome structure and they show that the helical struct...

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Autores principales: Gijeong Kim, Liyana Azmi, Seongmin Jang, Taeyang Jung, Hans Hebert, Andrew J. Roe, Olwyn Byron, Ji-Joon Song
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/bed36c0da3d94639a3797af3c65586f6
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