Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections

The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.

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Autores principales: Darshini Mahadevia, Rinki Saha, Alessia Manganaro, Nao Chuhma, Annette Ziolkowski-Blake, Ashlea A. Morgan, Dani Dumitriu, Stephen Rayport, Mark S. Ansorge
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd40
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spelling oai:doaj.org-article:bedb5a8b28ab4e4cadccee6c0020bd402021-11-28T12:35:42ZDopamine promotes aggression in mice via ventral tegmental area to lateral septum projections10.1038/s41467-021-27092-z2041-1723https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd402021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27092-zhttps://doaj.org/toc/2041-1723The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.Darshini MahadeviaRinki SahaAlessia ManganaroNao ChuhmaAnnette Ziolkowski-BlakeAshlea A. MorganDani DumitriuStephen RayportMark S. AnsorgeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Darshini Mahadevia
Rinki Saha
Alessia Manganaro
Nao Chuhma
Annette Ziolkowski-Blake
Ashlea A. Morgan
Dani Dumitriu
Stephen Rayport
Mark S. Ansorge
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
description The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.
format article
author Darshini Mahadevia
Rinki Saha
Alessia Manganaro
Nao Chuhma
Annette Ziolkowski-Blake
Ashlea A. Morgan
Dani Dumitriu
Stephen Rayport
Mark S. Ansorge
author_facet Darshini Mahadevia
Rinki Saha
Alessia Manganaro
Nao Chuhma
Annette Ziolkowski-Blake
Ashlea A. Morgan
Dani Dumitriu
Stephen Rayport
Mark S. Ansorge
author_sort Darshini Mahadevia
title Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
title_short Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
title_full Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
title_fullStr Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
title_full_unstemmed Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
title_sort dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd40
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