Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections
The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.
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Nature Portfolio
2021
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oai:doaj.org-article:bedb5a8b28ab4e4cadccee6c0020bd402021-11-28T12:35:42ZDopamine promotes aggression in mice via ventral tegmental area to lateral septum projections10.1038/s41467-021-27092-z2041-1723https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd402021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27092-zhttps://doaj.org/toc/2041-1723The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.Darshini MahadeviaRinki SahaAlessia ManganaroNao ChuhmaAnnette Ziolkowski-BlakeAshlea A. MorganDani DumitriuStephen RayportMark S. AnsorgeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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Science Q Darshini Mahadevia Rinki Saha Alessia Manganaro Nao Chuhma Annette Ziolkowski-Blake Ashlea A. Morgan Dani Dumitriu Stephen Rayport Mark S. Ansorge Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
description |
The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice. |
format |
article |
author |
Darshini Mahadevia Rinki Saha Alessia Manganaro Nao Chuhma Annette Ziolkowski-Blake Ashlea A. Morgan Dani Dumitriu Stephen Rayport Mark S. Ansorge |
author_facet |
Darshini Mahadevia Rinki Saha Alessia Manganaro Nao Chuhma Annette Ziolkowski-Blake Ashlea A. Morgan Dani Dumitriu Stephen Rayport Mark S. Ansorge |
author_sort |
Darshini Mahadevia |
title |
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
title_short |
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
title_full |
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
title_fullStr |
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
title_full_unstemmed |
Dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
title_sort |
dopamine promotes aggression in mice via ventral tegmental area to lateral septum projections |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd40 |
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