Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.

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Autores principales: Eva Malacaria, Giusj Monia Pugliese, Masayoshi Honda, Veronica Marabitti, Francesca Antonella Aiello, Maria Spies, Annapaola Franchitto, Pietro Pichierri
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c
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spelling oai:doaj.org-article:bedcee1b92964acbaf09d7d1347cc53c2021-12-02T17:01:27ZRad52 prevents excessive replication fork reversal and protects from nascent strand degradation10.1038/s41467-019-09196-92041-1723https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09196-9https://doaj.org/toc/2041-1723Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.Eva MalacariaGiusj Monia PuglieseMasayoshi HondaVeronica MarabittiFrancesca Antonella AielloMaria SpiesAnnapaola FranchittoPietro PichierriNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eva Malacaria
Giusj Monia Pugliese
Masayoshi Honda
Veronica Marabitti
Francesca Antonella Aiello
Maria Spies
Annapaola Franchitto
Pietro Pichierri
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
description Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.
format article
author Eva Malacaria
Giusj Monia Pugliese
Masayoshi Honda
Veronica Marabitti
Francesca Antonella Aiello
Maria Spies
Annapaola Franchitto
Pietro Pichierri
author_facet Eva Malacaria
Giusj Monia Pugliese
Masayoshi Honda
Veronica Marabitti
Francesca Antonella Aiello
Maria Spies
Annapaola Franchitto
Pietro Pichierri
author_sort Eva Malacaria
title Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
title_short Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
title_full Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
title_fullStr Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
title_full_unstemmed Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
title_sort rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c
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