Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.
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Nature Portfolio
2019
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oai:doaj.org-article:bedcee1b92964acbaf09d7d1347cc53c2021-12-02T17:01:27ZRad52 prevents excessive replication fork reversal and protects from nascent strand degradation10.1038/s41467-019-09196-92041-1723https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09196-9https://doaj.org/toc/2041-1723Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism.Eva MalacariaGiusj Monia PuglieseMasayoshi HondaVeronica MarabittiFrancesca Antonella AielloMaria SpiesAnnapaola FranchittoPietro PichierriNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-19 (2019) |
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Science Q |
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Science Q Eva Malacaria Giusj Monia Pugliese Masayoshi Honda Veronica Marabitti Francesca Antonella Aiello Maria Spies Annapaola Franchitto Pietro Pichierri Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
description |
Stabilisation of stalled replication forks prevents excessive fork reversal and genome instability. Here authors reveal a RAD52-dependent replication fork protection mechanism. |
format |
article |
author |
Eva Malacaria Giusj Monia Pugliese Masayoshi Honda Veronica Marabitti Francesca Antonella Aiello Maria Spies Annapaola Franchitto Pietro Pichierri |
author_facet |
Eva Malacaria Giusj Monia Pugliese Masayoshi Honda Veronica Marabitti Francesca Antonella Aiello Maria Spies Annapaola Franchitto Pietro Pichierri |
author_sort |
Eva Malacaria |
title |
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
title_short |
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
title_full |
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
title_fullStr |
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
title_full_unstemmed |
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
title_sort |
rad52 prevents excessive replication fork reversal and protects from nascent strand degradation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/bedcee1b92964acbaf09d7d1347cc53c |
work_keys_str_mv |
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_version_ |
1718382172778266624 |