Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy

Nanoparticle drug formulations are currently used as cancer treatment but the response in patients is highly variable. Here, the authors developed a Zirconium-89 nanoreporter able to predict using PET, therapeutic accumulation and efficacy of anti-cancer nanoparticle drug formulations when co-inject...

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Autores principales: Carlos Pérez-Medina, Dalya Abdel-Atti, Jun Tang, Yiming Zhao, Zahi A. Fayad, Jason S. Lewis, Willem J. M. Mulder, Thomas Reiner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/bedddcd02a6645ff8aef2ea1449bb3ee
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spelling oai:doaj.org-article:bedddcd02a6645ff8aef2ea1449bb3ee2021-12-02T14:40:16ZNanoreporter PET predicts the efficacy of anti-cancer nanotherapy10.1038/ncomms118382041-1723https://doaj.org/article/bedddcd02a6645ff8aef2ea1449bb3ee2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11838https://doaj.org/toc/2041-1723Nanoparticle drug formulations are currently used as cancer treatment but the response in patients is highly variable. Here, the authors developed a Zirconium-89 nanoreporter able to predict using PET, therapeutic accumulation and efficacy of anti-cancer nanoparticle drug formulations when co-injected in a murine breast cancer model.Carlos Pérez-MedinaDalya Abdel-AttiJun TangYiming ZhaoZahi A. FayadJason S. LewisWillem J. M. MulderThomas ReinerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carlos Pérez-Medina
Dalya Abdel-Atti
Jun Tang
Yiming Zhao
Zahi A. Fayad
Jason S. Lewis
Willem J. M. Mulder
Thomas Reiner
Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
description Nanoparticle drug formulations are currently used as cancer treatment but the response in patients is highly variable. Here, the authors developed a Zirconium-89 nanoreporter able to predict using PET, therapeutic accumulation and efficacy of anti-cancer nanoparticle drug formulations when co-injected in a murine breast cancer model.
format article
author Carlos Pérez-Medina
Dalya Abdel-Atti
Jun Tang
Yiming Zhao
Zahi A. Fayad
Jason S. Lewis
Willem J. M. Mulder
Thomas Reiner
author_facet Carlos Pérez-Medina
Dalya Abdel-Atti
Jun Tang
Yiming Zhao
Zahi A. Fayad
Jason S. Lewis
Willem J. M. Mulder
Thomas Reiner
author_sort Carlos Pérez-Medina
title Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
title_short Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
title_full Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
title_fullStr Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
title_full_unstemmed Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy
title_sort nanoreporter pet predicts the efficacy of anti-cancer nanotherapy
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/bedddcd02a6645ff8aef2ea1449bb3ee
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AT yimingzhao nanoreporterpetpredictstheefficacyofanticancernanotherapy
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