CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion. Here the authors show a role of CEACAM1 in promoting responsive CD8+ T cells in the context of a chronic lymphocytic choriomeningitis virus (...

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Autores principales:	Vishal Khairnar, Vikas Duhan, Ashwini M. Patil, Fan Zhou, Hilal Bhat, Christine Thoens, Piyush Sharma, Tom Adomati, Sarah-Kim Friendrich, Judith Bezgovsek, Janine D. Dreesen, Gunther Wennemuth, Astrid M. Westendorf, Gennadiy Zelinskyy, Ulf Dittmer, Cornelia Hardt, Jörg Timm, Joachim R. Göthert, Philipp A. Lang, Bernhard B. Singer, Karl S. Lang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bede592b38dd44ccaefbb07e0a9f1236
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spelling	oai:doaj.org-article:bede592b38dd44ccaefbb07e0a9f12362021-12-02T16:49:23ZCEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection10.1038/s41467-018-04832-22041-1723https://doaj.org/article/bede592b38dd44ccaefbb07e0a9f12362018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04832-2https://doaj.org/toc/2041-1723Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion. Here the authors show a role of CEACAM1 in promoting responsive CD8+ T cells in the context of a chronic lymphocytic choriomeningitis virus (LCMV) infection model.Vishal KhairnarVikas DuhanAshwini M. PatilFan ZhouHilal BhatChristine ThoensPiyush SharmaTom AdomatiSarah-Kim FriendrichJudith BezgovsekJanine D. DreesenGunther WennemuthAstrid M. WestendorfGennadiy ZelinskyyUlf DittmerCornelia HardtJörg TimmJoachim R. GöthertPhilipp A. LangBernhard B. SingerKarl S. LangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vishal Khairnar Vikas Duhan Ashwini M. Patil Fan Zhou Hilal Bhat Christine Thoens Piyush Sharma Tom Adomati Sarah-Kim Friendrich Judith Bezgovsek Janine D. Dreesen Gunther Wennemuth Astrid M. Westendorf Gennadiy Zelinskyy Ulf Dittmer Cornelia Hardt Jörg Timm Joachim R. Göthert Philipp A. Lang Bernhard B. Singer Karl S. Lang CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
description	Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion. Here the authors show a role of CEACAM1 in promoting responsive CD8+ T cells in the context of a chronic lymphocytic choriomeningitis virus (LCMV) infection model.
format	article
author	Vishal Khairnar Vikas Duhan Ashwini M. Patil Fan Zhou Hilal Bhat Christine Thoens Piyush Sharma Tom Adomati Sarah-Kim Friendrich Judith Bezgovsek Janine D. Dreesen Gunther Wennemuth Astrid M. Westendorf Gennadiy Zelinskyy Ulf Dittmer Cornelia Hardt Jörg Timm Joachim R. Göthert Philipp A. Lang Bernhard B. Singer Karl S. Lang
author_facet	Vishal Khairnar Vikas Duhan Ashwini M. Patil Fan Zhou Hilal Bhat Christine Thoens Piyush Sharma Tom Adomati Sarah-Kim Friendrich Judith Bezgovsek Janine D. Dreesen Gunther Wennemuth Astrid M. Westendorf Gennadiy Zelinskyy Ulf Dittmer Cornelia Hardt Jörg Timm Joachim R. Göthert Philipp A. Lang Bernhard B. Singer Karl S. Lang
author_sort	Vishal Khairnar
title	CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
title_short	CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
title_full	CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
title_fullStr	CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
title_full_unstemmed	CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
title_sort	ceacam1 promotes cd8+ t cell responses and improves control of a chronic viral infection
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bede592b38dd44ccaefbb07e0a9f1236
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CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

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