LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syntenic regions in mouse, rat and human with diverge...

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Main Authors:	Julie Brind’Amour, Hisato Kobayashi, Julien Richard Albert, Kenjiro Shirane, Akihiko Sakashita, Asuka Kamio, Aaron Bogutz, Tasuku Koike, Mohammad M. Karimi, Louis Lefebvre, Tomohiro Kono, Matthew C. Lorincz
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/bee0bd7cd38c4fa6acd4a2ae886f0f09
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spelling	oai:doaj.org-article:bee0bd7cd38c4fa6acd4a2ae886f0f092021-12-02T16:56:55ZLTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation10.1038/s41467-018-05841-x2041-1723https://doaj.org/article/bee0bd7cd38c4fa6acd4a2ae886f0f092018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05841-xhttps://doaj.org/toc/2041-1723De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syntenic regions in mouse, rat and human with divergent DNA methylation associated with private LITs.Julie Brind’AmourHisato KobayashiJulien Richard AlbertKenjiro ShiraneAkihiko SakashitaAsuka KamioAaron BogutzTasuku KoikeMohammad M. KarimiLouis LefebvreTomohiro KonoMatthew C. LorinczNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julie Brind’Amour Hisato Kobayashi Julien Richard Albert Kenjiro Shirane Akihiko Sakashita Asuka Kamio Aaron Bogutz Tasuku Koike Mohammad M. Karimi Louis Lefebvre Tomohiro Kono Matthew C. Lorincz LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
description	De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syntenic regions in mouse, rat and human with divergent DNA methylation associated with private LITs.
format	article
author	Julie Brind’Amour Hisato Kobayashi Julien Richard Albert Kenjiro Shirane Akihiko Sakashita Asuka Kamio Aaron Bogutz Tasuku Koike Mohammad M. Karimi Louis Lefebvre Tomohiro Kono Matthew C. Lorincz
author_facet	Julie Brind’Amour Hisato Kobayashi Julien Richard Albert Kenjiro Shirane Akihiko Sakashita Asuka Kamio Aaron Bogutz Tasuku Koike Mohammad M. Karimi Louis Lefebvre Tomohiro Kono Matthew C. Lorincz
author_sort	Julie Brind’Amour
title	LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
title_short	LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
title_full	LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
title_fullStr	LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
title_full_unstemmed	LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
title_sort	ltr retrotransposons transcribed in oocytes drive species-specific and heritable changes in dna methylation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bee0bd7cd38c4fa6acd4a2ae886f0f09
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LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

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