Crowdsourcing Our National Gut

ABSTRACT The microbes of the human intestinal tract play a profound role in our health. The complex interactions between our gut microbial communities and the external environment, and the resulting functional consequences, can be difficult to disentangle. To address this problem, McDonald et al. (m...

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Autores principales:	Laura E. Grieneisen, Ran Blekhman
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	American Gut Project citizen science gut microbiome metabolome Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/bee2a8fd04c241fa8a11c6fb9ba863cc
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spelling	oai:doaj.org-article:bee2a8fd04c241fa8a11c6fb9ba863cc2021-12-02T18:15:44ZCrowdsourcing Our National Gut10.1128/mSystems.00060-182379-5077https://doaj.org/article/bee2a8fd04c241fa8a11c6fb9ba863cc2018-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00060-18https://doaj.org/toc/2379-5077ABSTRACT The microbes of the human intestinal tract play a profound role in our health. The complex interactions between our gut microbial communities and the external environment, and the resulting functional consequences, can be difficult to disentangle. To address this problem, McDonald et al. (mSystems 3:e00031-18, 2018, https://doi.org/10.1128/mSystems.00031-18) present the first set of results from the American Gut Project, a citizen science-based data set currently comprised of over 10,000 gut microbiome samples and associated life history data. By combining this extensive data set with other published studies, the authors uncover novel relationships between gut microbiome structure and function. For example, they found that dietary plant diversity and recent antibiotic use predict both microbial and metabolomic diversity. McDonald et al. also demonstrate that there is high diversity across human gut microbiomes, even compared to the diversity of environmental microbiomes. The results from this study illuminate the potential of the citizen science approach to further our knowledge of host-associated microbial communities.Laura E. GrieneisenRan BlekhmanAmerican Society for MicrobiologyarticleAmerican Gut Projectcitizen sciencegut microbiomemetabolomeMicrobiologyQR1-502ENmSystems, Vol 3, Iss 3 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	American Gut Project citizen science gut microbiome metabolome Microbiology QR1-502
spellingShingle	American Gut Project citizen science gut microbiome metabolome Microbiology QR1-502 Laura E. Grieneisen Ran Blekhman Crowdsourcing Our National Gut
description	ABSTRACT The microbes of the human intestinal tract play a profound role in our health. The complex interactions between our gut microbial communities and the external environment, and the resulting functional consequences, can be difficult to disentangle. To address this problem, McDonald et al. (mSystems 3:e00031-18, 2018, https://doi.org/10.1128/mSystems.00031-18) present the first set of results from the American Gut Project, a citizen science-based data set currently comprised of over 10,000 gut microbiome samples and associated life history data. By combining this extensive data set with other published studies, the authors uncover novel relationships between gut microbiome structure and function. For example, they found that dietary plant diversity and recent antibiotic use predict both microbial and metabolomic diversity. McDonald et al. also demonstrate that there is high diversity across human gut microbiomes, even compared to the diversity of environmental microbiomes. The results from this study illuminate the potential of the citizen science approach to further our knowledge of host-associated microbial communities.
format	article
author	Laura E. Grieneisen Ran Blekhman
author_facet	Laura E. Grieneisen Ran Blekhman
author_sort	Laura E. Grieneisen
title	Crowdsourcing Our National Gut
title_short	Crowdsourcing Our National Gut
title_full	Crowdsourcing Our National Gut
title_fullStr	Crowdsourcing Our National Gut
title_full_unstemmed	Crowdsourcing Our National Gut
title_sort	crowdsourcing our national gut
publisher	American Society for Microbiology
publishDate	2018
url	https://doaj.org/article/bee2a8fd04c241fa8a11c6fb9ba863cc
work_keys_str_mv	AT lauraegrieneisen crowdsourcingournationalgut AT ranblekhman crowdsourcingournationalgut
_version_	1718378358097575936

Crowdsourcing Our National Gut

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