Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence of <named-content content-type="genus-species">Streptococcus pyogenes</named-content>

ABSTRACT Serum opacity factor (SOF) is a cell surface virulence factor made by the human pathogen Streptococcus pyogenes. We found that S. pyogenes strains with naturally occurring truncation mutations in the sof gene have markedly enhanced beta-hemolysis. Moreover, deletion of the sof gene in a SOF...

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Bibliographic Details
Main Authors: Luchang Zhu, Randall J. Olsen, James M. Musser
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/beeeb39dcb5b4ce9a158a3854f9701b7
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