Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery

Polymer-based systems are often considered a necessity for controlled drug delivery, but have well-known limitations. Here, the authors report on drug delivery implants formed solely from corticosteroid dimers, which demonstrate controlled release and overcome many of the challenges of polymer-based...

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Autores principales:	Kyle Battiston, Ian Parrag, Matthew Statham, Dimitra Louka, Hans Fischer, Gillian Mackey, Adam Daley, Fan Gu, Emily Baldwin, Bingqing Yang, Ben Muirhead, Emily Anne Hicks, Heather Sheardown, Leonid Kalachev, Christopher Crean, Jeffrey Edelman, J. Paul Santerre, Wendy Naimark
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bef9dd810b064602859deb552da70df7
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spelling	oai:doaj.org-article:bef9dd810b064602859deb552da70df72021-12-02T15:45:30ZPolymer-free corticosteroid dimer implants for controlled and sustained drug delivery10.1038/s41467-021-23232-72041-1723https://doaj.org/article/bef9dd810b064602859deb552da70df72021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23232-7https://doaj.org/toc/2041-1723Polymer-based systems are often considered a necessity for controlled drug delivery, but have well-known limitations. Here, the authors report on drug delivery implants formed solely from corticosteroid dimers, which demonstrate controlled release and overcome many of the challenges of polymer-based systems.Kyle BattistonIan ParragMatthew StathamDimitra LoukaHans FischerGillian MackeyAdam DaleyFan GuEmily BaldwinBingqing YangBen MuirheadEmily Anne HicksHeather SheardownLeonid KalachevChristopher CreanJeffrey EdelmanJ. Paul SanterreWendy NaimarkNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyle Battiston Ian Parrag Matthew Statham Dimitra Louka Hans Fischer Gillian Mackey Adam Daley Fan Gu Emily Baldwin Bingqing Yang Ben Muirhead Emily Anne Hicks Heather Sheardown Leonid Kalachev Christopher Crean Jeffrey Edelman J. Paul Santerre Wendy Naimark Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
description	Polymer-based systems are often considered a necessity for controlled drug delivery, but have well-known limitations. Here, the authors report on drug delivery implants formed solely from corticosteroid dimers, which demonstrate controlled release and overcome many of the challenges of polymer-based systems.
format	article
author	Kyle Battiston Ian Parrag Matthew Statham Dimitra Louka Hans Fischer Gillian Mackey Adam Daley Fan Gu Emily Baldwin Bingqing Yang Ben Muirhead Emily Anne Hicks Heather Sheardown Leonid Kalachev Christopher Crean Jeffrey Edelman J. Paul Santerre Wendy Naimark
author_facet	Kyle Battiston Ian Parrag Matthew Statham Dimitra Louka Hans Fischer Gillian Mackey Adam Daley Fan Gu Emily Baldwin Bingqing Yang Ben Muirhead Emily Anne Hicks Heather Sheardown Leonid Kalachev Christopher Crean Jeffrey Edelman J. Paul Santerre Wendy Naimark
author_sort	Kyle Battiston
title	Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
title_short	Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
title_full	Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
title_fullStr	Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
title_full_unstemmed	Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
title_sort	polymer-free corticosteroid dimer implants for controlled and sustained drug delivery
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bef9dd810b064602859deb552da70df7
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Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery

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