MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling

MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling

The aim of this study was to identify novel microRNAs related to obstructive sleep apnea (OSA) characterized by intermittent hypoxia with re-oxygenation (IHR) injury. Illumina MiSeq was used to identify OSA-associated microRNAs, which were validated in an independent cohort. The interaction between...

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Autores principales: Yung-Che Chen, Po-Yuan Hsu, Mao-Chang Su, Ting-Wen Chen, Chang-Chun Hsiao, Chien-Hung Chin, Chia-Wei Liou, Po-Wen Wang, Ting-Ya Wang, Yong-Yong Lin, Chiu-Ping Lee, Meng-Chih Lin
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
obstructive sleep apnea
microRNA
next generation sequencing
miR-92b
miR-15b
PTGS1
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/befe855373cd4e1e90ad97646c118855
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