Sis1 potentiates the stress response to protein aggregation and elevated temperature

Identifying factors that enable cells to induce a potent stress response to amyloid-like aggregation can provide further insight into the mechanism of stress regulation. Here, the authors express polyglutamine-expanded Huntingtin as a model disease protein in yeast cells and perform a genetic screen...

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Autores principales: Courtney L. Klaips, Michael H. M. Gropp, Mark S. Hipp, F. Ulrich Hartl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bf06109c704f419bbd81a8c23509df78
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