Sis1 potentiates the stress response to protein aggregation and elevated temperature
Identifying factors that enable cells to induce a potent stress response to amyloid-like aggregation can provide further insight into the mechanism of stress regulation. Here, the authors express polyglutamine-expanded Huntingtin as a model disease protein in yeast cells and perform a genetic screen...
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Autores principales: | Courtney L. Klaips, Michael H. M. Gropp, Mark S. Hipp, F. Ulrich Hartl |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/bf06109c704f419bbd81a8c23509df78 |
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