A cross-species assessment of behavioral flexibility in compulsive disorders

Nabil Benzina et al. use a reversal learning task to examine behavioral flexibility in human and mouse models of obsessive compulsive disorder (OCD). They report that only subsets of human patients or OCD-like mice show deficits in behavioral flexibility, highlighting the diverse presentation of cog...

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Autores principales: Nabil Benzina, Karim N’Diaye, Antoine Pelissolo, Luc Mallet, Eric Burguière
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bf203c13df764bb8980102de4e6c90be
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spelling oai:doaj.org-article:bf203c13df764bb8980102de4e6c90be2021-12-02T13:51:05ZA cross-species assessment of behavioral flexibility in compulsive disorders10.1038/s42003-020-01611-y2399-3642https://doaj.org/article/bf203c13df764bb8980102de4e6c90be2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01611-yhttps://doaj.org/toc/2399-3642Nabil Benzina et al. use a reversal learning task to examine behavioral flexibility in human and mouse models of obsessive compulsive disorder (OCD). They report that only subsets of human patients or OCD-like mice show deficits in behavioral flexibility, highlighting the diverse presentation of cognitive deficits in compulsive disorders.Nabil BenzinaKarim N’DiayeAntoine PelissoloLuc MalletEric BurguièreNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Nabil Benzina
Karim N’Diaye
Antoine Pelissolo
Luc Mallet
Eric Burguière
A cross-species assessment of behavioral flexibility in compulsive disorders
description Nabil Benzina et al. use a reversal learning task to examine behavioral flexibility in human and mouse models of obsessive compulsive disorder (OCD). They report that only subsets of human patients or OCD-like mice show deficits in behavioral flexibility, highlighting the diverse presentation of cognitive deficits in compulsive disorders.
format article
author Nabil Benzina
Karim N’Diaye
Antoine Pelissolo
Luc Mallet
Eric Burguière
author_facet Nabil Benzina
Karim N’Diaye
Antoine Pelissolo
Luc Mallet
Eric Burguière
author_sort Nabil Benzina
title A cross-species assessment of behavioral flexibility in compulsive disorders
title_short A cross-species assessment of behavioral flexibility in compulsive disorders
title_full A cross-species assessment of behavioral flexibility in compulsive disorders
title_fullStr A cross-species assessment of behavioral flexibility in compulsive disorders
title_full_unstemmed A cross-species assessment of behavioral flexibility in compulsive disorders
title_sort cross-species assessment of behavioral flexibility in compulsive disorders
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bf203c13df764bb8980102de4e6c90be
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