Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susc...

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Autores principales:	Manuel A. Ferreira, Eric R. Gamazon, Fares Al-Ejeh, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton-Culver, Adalgeir Arason, Volker Arndt, Kristan J. Aronson, Banu K. Arun, Ella Asseryanis, Jacopo Azzollini, Judith Balmaña, Daniel R. Barnes, Daniel Barrowdale, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Katarzyna Białkowska, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Ake Borg, Hiltrud Brauch, Hermann Brenner, Annegien Broeks, Barbara Burwinkel, Trinidad Caldés, Maria A. Caligo, Daniele Campa, Ian Campbell, Federico Canzian, Jonathan Carter, Brian D. Carter, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Hans Christiansen, Wendy K. Chung, Kathleen B. M. Claes, Christine L. Clarke, EMBRACE Collaborators, GC-HBOC Study Collaborators, GEMO Study Collaborators, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Miguel de la Hoya, Joe Dennis, Peter Devilee, Orland Diez, Thilo Dörk, Alison M. Dunning, Miriam Dwek, Diana M. Eccles, Bent Ejlertsen, Carolina Ellberg, Christoph Engel, Mikael Eriksson, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Eitan Friedman, Debra Frost, Marike Gabrielson, Manuela Gago-Dominguez, Patricia A. Ganz, Susan M. Gapstur, Judy Garber, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Graham G. Giles, Gord Glendon, Andrew K. Godwin, Mark S. Goldberg, David E. Goldgar, Anna González-Neira, Mark H. Greene, Jacek Gronwald, Pascal Guénel, Christopher A. Haiman, Per Hall, Ute Hamann, Wei He, Jane Heyworth, Frans B. L. Hogervorst, Antoinette Hollestelle, Robert N. Hoover, John L. Hopper, Peter J. Hulick, Keith Humphreys, Evgeny N. Imyanitov, ABCTB Investigators, HEBON Investigators, BCFR Investigators, Claudine Isaacs, Milena Jakimovska, Anna Jakubowska, Paul A. James, Ramunas Janavicius, Rachel C. Jankowitz, Esther M. John, Nichola Johnson, Vijai Joseph, Beth Y. Karlan, Elza Khusnutdinova, Johanna I. Kiiski, Yon-Dschun Ko, Michael E. Jones, Irene Konstantopoulou, Vessela N. Kristensen, Yael Laitman, Diether Lambrechts, Conxi Lazaro, Goska Leslie, Jenny Lester, Fabienne Lesueur, Sara Lindström, Jirong Long, Jennifer T. Loud, Jan Lubiński, Enes Makalic, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Tabea Maurer, Dimitrios Mavroudis, Lesley McGuffog, Alfons Meindl, Usha Menon, Kyriaki Michailidou, Austin Miller, Marco Montagna, Fernando Moreno, Lidia Moserle, Anna Marie Mulligan, Katherine L. Nathanson, Susan L. Neuhausen, Heli Nevanlinna, Ines Nevelsteen, Finn C. Nielsen, Liene Nikitina-Zake, Robert L. Nussbaum, Kenneth Offit, Edith Olah, Olufunmilayo I. Olopade, Håkan Olsson, Ana Osorio, Janos Papp, Tjoung-Won Park-Simon, Michael T. Parsons, Inge Sokilde Pedersen, Ana Peixoto, Paolo Peterlongo, Paul D. P. Pharoah, Dijana Plaseska-Karanfilska, Bruce Poppe, Nadege Presneau, Paolo Radice, Johanna Rantala, Gad Rennert, Harvey A. Risch, Emmanouil Saloustros, Kristin Sanden, Elinor J. Sawyer, Marjanka K. Schmidt, Rita K. Schmutzler, Priyanka Sharma, Xiao-Ou Shu, Jacques Simard, Christian F. Singer, Penny Soucy, Melissa C. Southey, John J. Spinelli, Amanda B. Spurdle, Jennifer Stone, Anthony J. Swerdlow, William J. Tapper, Jack A. Taylor, Manuel R. Teixeira, Mary Beth Terry, Alex Teulé, Mads Thomassen, Kathrin Thöne, Darcy L. Thull, Marc Tischkowitz, Amanda E. Toland, Diana Torres, Thérèse Truong, Nadine Tung, Celine M. Vachon, Christi J. van Asperen, Ans M. W. van den Ouweland, Elizabeth J. van Rensburg, Ana Vega, Alessandra Viel, Qin Wang, Barbara Wappenschmidt, Jeffrey N. Weitzel, Camilla Wendt, Robert Winqvist, Xiaohong R. Yang, Drakoulis Yannoukakos, Argyrios Ziogas, Peter Kraft, Antonis C. Antoniou, Wei Zheng, Douglas F. Easton, Roger L. Milne, Jonathan Beesley, Georgia Chenevix-Trench
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bf21d4862d3747ff97f6117d701a4866
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id	oai:doaj.org-article:bf21d4862d3747ff97f6117d701a4866
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institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Manuel A. Ferreira Eric R. Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L. Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J. Aronson Banu K. Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R. Barnes Daniel Barrowdale Matthias W. Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V. Bogdanova Stig E. Bojesen Manjeet K. Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A. Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D. Carter Jose E. Castelao Jenny Chang-Claude Stephen J. Chanock Hans Christiansen Wendy K. Chung Kathleen B. M. Claes Christine L. Clarke EMBRACE Collaborators GC-HBOC Study Collaborators GEMO Study Collaborators Fergus J. Couch Angela Cox Simon S. Cross Kamila Czene Mary B. Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M. Dunning Miriam Dwek Diana M. Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A. Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A. Ganz Susan M. Gapstur Judy Garber Montserrat García-Closas José A. García-Sáenz Mia M. Gaudet Graham G. Giles Gord Glendon Andrew K. Godwin Mark S. Goldberg David E. Goldgar Anna González-Neira Mark H. Greene Jacek Gronwald Pascal Guénel Christopher A. Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B. L. Hogervorst Antoinette Hollestelle Robert N. Hoover John L. Hopper Peter J. Hulick Keith Humphreys Evgeny N. Imyanitov ABCTB Investigators HEBON Investigators BCFR Investigators Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A. James Ramunas Janavicius Rachel C. Jankowitz Esther M. John Nichola Johnson Vijai Joseph Beth Y. Karlan Elza Khusnutdinova Johanna I. Kiiski Yon-Dschun Ko Michael E. Jones Irene Konstantopoulou Vessela N. Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T. Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L. Nathanson Susan L. Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C. Nielsen Liene Nikitina-Zake Robert L. Nussbaum Kenneth Offit Edith Olah Olufunmilayo I. Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T. Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D. P. Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A. Risch Emmanouil Saloustros Kristin Sanden Elinor J. Sawyer Marjanka K. Schmidt Rita K. Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F. Singer Penny Soucy Melissa C. Southey John J. Spinelli Amanda B. Spurdle Jennifer Stone Anthony J. Swerdlow William J. Tapper Jack A. Taylor Manuel R. Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L. Thull Marc Tischkowitz Amanda E. Toland Diana Torres Thérèse Truong Nadine Tung Celine M. Vachon Christi J. van Asperen Ans M. W. van den Ouweland Elizabeth J. van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N. Weitzel Camilla Wendt Robert Winqvist Xiaohong R. Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C. Antoniou Wei Zheng Douglas F. Easton Roger L. Milne Jonathan Beesley Georgia Chenevix-Trench Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
description	Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.
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author	Manuel A. Ferreira Eric R. Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L. Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J. Aronson Banu K. Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R. Barnes Daniel Barrowdale Matthias W. Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V. Bogdanova Stig E. Bojesen Manjeet K. Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A. Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D. Carter Jose E. Castelao Jenny Chang-Claude Stephen J. Chanock Hans Christiansen Wendy K. Chung Kathleen B. M. Claes Christine L. Clarke EMBRACE Collaborators GC-HBOC Study Collaborators GEMO Study Collaborators Fergus J. Couch Angela Cox Simon S. Cross Kamila Czene Mary B. Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M. Dunning Miriam Dwek Diana M. Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A. Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A. Ganz Susan M. Gapstur Judy Garber Montserrat García-Closas José A. García-Sáenz Mia M. Gaudet Graham G. Giles Gord Glendon Andrew K. Godwin Mark S. Goldberg David E. Goldgar Anna González-Neira Mark H. Greene Jacek Gronwald Pascal Guénel Christopher A. Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B. L. Hogervorst Antoinette Hollestelle Robert N. Hoover John L. Hopper Peter J. Hulick Keith Humphreys Evgeny N. Imyanitov ABCTB Investigators HEBON Investigators BCFR Investigators Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A. James Ramunas Janavicius Rachel C. Jankowitz Esther M. John Nichola Johnson Vijai Joseph Beth Y. Karlan Elza Khusnutdinova Johanna I. Kiiski Yon-Dschun Ko Michael E. Jones Irene Konstantopoulou Vessela N. Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T. Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L. Nathanson Susan L. Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C. Nielsen Liene Nikitina-Zake Robert L. Nussbaum Kenneth Offit Edith Olah Olufunmilayo I. Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T. Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D. P. Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A. Risch Emmanouil Saloustros Kristin Sanden Elinor J. Sawyer Marjanka K. Schmidt Rita K. Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F. Singer Penny Soucy Melissa C. Southey John J. Spinelli Amanda B. Spurdle Jennifer Stone Anthony J. Swerdlow William J. Tapper Jack A. Taylor Manuel R. Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L. Thull Marc Tischkowitz Amanda E. Toland Diana Torres Thérèse Truong Nadine Tung Celine M. Vachon Christi J. van Asperen Ans M. W. van den Ouweland Elizabeth J. van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N. Weitzel Camilla Wendt Robert Winqvist Xiaohong R. Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C. Antoniou Wei Zheng Douglas F. Easton Roger L. Milne Jonathan Beesley Georgia Chenevix-Trench
author_facet	Manuel A. Ferreira Eric R. Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L. Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J. Aronson Banu K. Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R. Barnes Daniel Barrowdale Matthias W. Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V. Bogdanova Stig E. Bojesen Manjeet K. Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A. Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D. Carter Jose E. Castelao Jenny Chang-Claude Stephen J. Chanock Hans Christiansen Wendy K. Chung Kathleen B. M. Claes Christine L. Clarke EMBRACE Collaborators GC-HBOC Study Collaborators GEMO Study Collaborators Fergus J. Couch Angela Cox Simon S. Cross Kamila Czene Mary B. Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M. Dunning Miriam Dwek Diana M. Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A. Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A. Ganz Susan M. Gapstur Judy Garber Montserrat García-Closas José A. García-Sáenz Mia M. Gaudet Graham G. Giles Gord Glendon Andrew K. Godwin Mark S. Goldberg David E. Goldgar Anna González-Neira Mark H. Greene Jacek Gronwald Pascal Guénel Christopher A. Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B. L. Hogervorst Antoinette Hollestelle Robert N. Hoover John L. Hopper Peter J. Hulick Keith Humphreys Evgeny N. Imyanitov ABCTB Investigators HEBON Investigators BCFR Investigators Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A. James Ramunas Janavicius Rachel C. Jankowitz Esther M. John Nichola Johnson Vijai Joseph Beth Y. Karlan Elza Khusnutdinova Johanna I. Kiiski Yon-Dschun Ko Michael E. Jones Irene Konstantopoulou Vessela N. Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T. Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L. Nathanson Susan L. Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C. Nielsen Liene Nikitina-Zake Robert L. Nussbaum Kenneth Offit Edith Olah Olufunmilayo I. Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T. Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D. P. Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A. Risch Emmanouil Saloustros Kristin Sanden Elinor J. Sawyer Marjanka K. Schmidt Rita K. Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F. Singer Penny Soucy Melissa C. Southey John J. Spinelli Amanda B. Spurdle Jennifer Stone Anthony J. Swerdlow William J. Tapper Jack A. Taylor Manuel R. Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L. Thull Marc Tischkowitz Amanda E. Toland Diana Torres Thérèse Truong Nadine Tung Celine M. Vachon Christi J. van Asperen Ans M. W. van den Ouweland Elizabeth J. van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N. Weitzel Camilla Wendt Robert Winqvist Xiaohong R. Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C. Antoniou Wei Zheng Douglas F. Easton Roger L. Milne Jonathan Beesley Georgia Chenevix-Trench
author_sort	Manuel A. Ferreira
title	Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
title_short	Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
title_full	Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
title_fullStr	Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
title_full_unstemmed	Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
title_sort	genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bf21d4862d3747ff97f6117d701a4866
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spelling	oai:doaj.org-article:bf21d4862d3747ff97f6117d701a48662021-12-02T15:35:36ZGenome-wide association and transcriptome studies identify target genes and risk loci for breast cancer10.1038/s41467-018-08053-52041-1723https://doaj.org/article/bf21d4862d3747ff97f6117d701a48662019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08053-5https://doaj.org/toc/2041-1723Over 170 susceptibility loci have been identified by genome-wide association studies in breast cancer. Here, the authors interrogated the role of risk-associated variants from non-breast tissue, and using expression quantitative trait loci, identify potential target genes of known breast cancer susceptibility variants, as well as 11 regions not previously known to be associated with breast cancer risk.Manuel A. FerreiraEric R. GamazonFares Al-EjehKristiina AittomäkiIrene L. AndrulisHoda Anton-CulverAdalgeir ArasonVolker ArndtKristan J. AronsonBanu K. ArunElla AsseryanisJacopo AzzolliniJudith BalmañaDaniel R. BarnesDaniel BarrowdaleMatthias W. BeckmannSabine BehrensJavier BenitezMarina BermishevaKatarzyna BiałkowskaCarl BlomqvistNatalia V. BogdanovaStig E. BojesenManjeet K. BollaAke BorgHiltrud BrauchHermann BrennerAnnegien BroeksBarbara BurwinkelTrinidad CaldésMaria A. CaligoDaniele CampaIan CampbellFederico CanzianJonathan CarterBrian D. CarterJose E. CastelaoJenny Chang-ClaudeStephen J. ChanockHans ChristiansenWendy K. ChungKathleen B. M. ClaesChristine L. ClarkeEMBRACE CollaboratorsGC-HBOC Study CollaboratorsGEMO Study CollaboratorsFergus J. CouchAngela CoxSimon S. CrossKamila CzeneMary B. DalyMiguel de la HoyaJoe DennisPeter DevileeOrland DiezThilo DörkAlison M. DunningMiriam DwekDiana M. EcclesBent EjlertsenCarolina EllbergChristoph EngelMikael ErikssonPeter A. FaschingOlivia FletcherHenrik FlygerEitan FriedmanDebra FrostMarike GabrielsonManuela Gago-DominguezPatricia A. GanzSusan M. GapsturJudy GarberMontserrat García-ClosasJosé A. García-SáenzMia M. GaudetGraham G. GilesGord GlendonAndrew K. GodwinMark S. GoldbergDavid E. GoldgarAnna González-NeiraMark H. GreeneJacek GronwaldPascal GuénelChristopher A. HaimanPer HallUte HamannWei HeJane HeyworthFrans B. L. HogervorstAntoinette HollestelleRobert N. HooverJohn L. HopperPeter J. HulickKeith HumphreysEvgeny N. ImyanitovABCTB InvestigatorsHEBON InvestigatorsBCFR InvestigatorsClaudine IsaacsMilena JakimovskaAnna JakubowskaPaul A. JamesRamunas JanaviciusRachel C. JankowitzEsther M. JohnNichola JohnsonVijai JosephBeth Y. KarlanElza KhusnutdinovaJohanna I. KiiskiYon-Dschun KoMichael E. JonesIrene KonstantopoulouVessela N. KristensenYael LaitmanDiether LambrechtsConxi LazaroGoska LeslieJenny LesterFabienne LesueurSara LindströmJirong LongJennifer T. LoudJan LubińskiEnes MakalicArto MannermaaMehdi ManoochehriSara MargolinTabea MaurerDimitrios MavroudisLesley McGuffogAlfons MeindlUsha MenonKyriaki MichailidouAustin MillerMarco MontagnaFernando MorenoLidia MoserleAnna Marie MulliganKatherine L. NathansonSusan L. NeuhausenHeli NevanlinnaInes NevelsteenFinn C. NielsenLiene Nikitina-ZakeRobert L. NussbaumKenneth OffitEdith OlahOlufunmilayo I. OlopadeHåkan OlssonAna OsorioJanos PappTjoung-Won Park-SimonMichael T. ParsonsInge Sokilde PedersenAna PeixotoPaolo PeterlongoPaul D. P. PharoahDijana Plaseska-KaranfilskaBruce PoppeNadege PresneauPaolo RadiceJohanna RantalaGad RennertHarvey A. RischEmmanouil SaloustrosKristin SandenElinor J. SawyerMarjanka K. SchmidtRita K. SchmutzlerPriyanka SharmaXiao-Ou ShuJacques SimardChristian F. SingerPenny SoucyMelissa C. SoutheyJohn J. SpinelliAmanda B. SpurdleJennifer StoneAnthony J. SwerdlowWilliam J. TapperJack A. TaylorManuel R. TeixeiraMary Beth TerryAlex TeuléMads ThomassenKathrin ThöneDarcy L. ThullMarc TischkowitzAmanda E. TolandDiana TorresThérèse TruongNadine TungCeline M. VachonChristi J. van AsperenAns M. W. van den OuwelandElizabeth J. van RensburgAna VegaAlessandra VielQin WangBarbara WappenschmidtJeffrey N. WeitzelCamilla WendtRobert WinqvistXiaohong R. YangDrakoulis YannoukakosArgyrios ZiogasPeter KraftAntonis C. AntoniouWei ZhengDouglas F. EastonRoger L. MilneJonathan BeesleyGeorgia Chenevix-TrenchNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

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