A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients

Li-Fen Chen,1 Ching-En Lin,1–3 Yu-Ching Chou,4 Wei-Chung Mao,1,5 Yi-Chyan Chen,1–3 Nian-Sheng Tzeng1,6 1Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei City, Taiwan; 2Taipei Tzu Chi Hospital, The Buddhist Medical...

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Autores principales: Chen LF, Lin CE, Chou YC, Mao WC, Chen YC, Tzeng NS
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:bf2ce716c90b4f7c9e79bde8a44042422021-12-02T06:50:00ZA comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients1176-63281178-2021https://doaj.org/article/bf2ce716c90b4f7c9e79bde8a44042422013-08-01T00:00:00Zhttp://www.dovepress.com/a-comparison-of-complex-sleep-behaviors-with-two-short-acting-z-hypnos-a13991https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Li-Fen Chen,1 Ching-En Lin,1–3 Yu-Ching Chou,4 Wei-Chung Mao,1,5 Yi-Chyan Chen,1–3 Nian-Sheng Tzeng1,6 1Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei City, Taiwan; 2Taipei Tzu Chi Hospital, The Buddhist Medical Foundation, Taipei, Taiwan; 3School of Medicine, Tzu Chi University, Hualien, Taiwan; 4School of Public Health, National Defense Medical Center, Taipei City, Taiwan; 5Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei City, Taiwan; 6Student Counseling Center, National Defense Medical Center, Taipei City, Taiwan Objective: Complex sleep behaviors (CSBs) are classified as “parasomnias” in the International Classification of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients in Taiwan. Methods: Subjects (N = 1,220) using zolpidem or zopiclone were enrolled from the psychiatric outpatient clinics of a medical center in Taiwan over a 16-month period in 2006–2007. Subjects with zolpidem (N = 1,132) and subjects with zopiclone (N = 88) were analyzed. All subjects completed a questionnaire that included demographic data and complex sleep behaviors after taking hypnotics. Results: Among zolpidem and zopiclone users, 3.28% of patients reported incidents of somnambulism or amnesic sleep-related behavior problems. The incidence of CSBs with zolpidem and zopiclone were 3.27%, and 3.41%, respectively, which was significantly lower than other studies in Taiwan. Conclusion: These results serve as a reminder for clinicians to make inquiries regarding any unusual performance of parasomnic activities when prescribing zolpidem or zopiclone. Keywords: parasomnia, somnambulism, amnesic sleep-related behavior, sleepwalking, zolpidem, zopicloneChen LFLin CEChou YCMao WCChen YCTzeng NSDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 1159-1162 (2013)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Chen LF
Lin CE
Chou YC
Mao WC
Chen YC
Tzeng NS
A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
description Li-Fen Chen,1 Ching-En Lin,1–3 Yu-Ching Chou,4 Wei-Chung Mao,1,5 Yi-Chyan Chen,1–3 Nian-Sheng Tzeng1,6 1Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei City, Taiwan; 2Taipei Tzu Chi Hospital, The Buddhist Medical Foundation, Taipei, Taiwan; 3School of Medicine, Tzu Chi University, Hualien, Taiwan; 4School of Public Health, National Defense Medical Center, Taipei City, Taiwan; 5Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei City, Taiwan; 6Student Counseling Center, National Defense Medical Center, Taipei City, Taiwan Objective: Complex sleep behaviors (CSBs) are classified as “parasomnias” in the International Classification of Sleep Disorders, Second Edition (ICSD-2). To realize the potential danger after taking two short-acting Z-hypnosedative drugs, we estimated the incidence of CSBs in nonpsychotic patients in Taiwan. Methods: Subjects (N = 1,220) using zolpidem or zopiclone were enrolled from the psychiatric outpatient clinics of a medical center in Taiwan over a 16-month period in 2006–2007. Subjects with zolpidem (N = 1,132) and subjects with zopiclone (N = 88) were analyzed. All subjects completed a questionnaire that included demographic data and complex sleep behaviors after taking hypnotics. Results: Among zolpidem and zopiclone users, 3.28% of patients reported incidents of somnambulism or amnesic sleep-related behavior problems. The incidence of CSBs with zolpidem and zopiclone were 3.27%, and 3.41%, respectively, which was significantly lower than other studies in Taiwan. Conclusion: These results serve as a reminder for clinicians to make inquiries regarding any unusual performance of parasomnic activities when prescribing zolpidem or zopiclone. Keywords: parasomnia, somnambulism, amnesic sleep-related behavior, sleepwalking, zolpidem, zopiclone
format article
author Chen LF
Lin CE
Chou YC
Mao WC
Chen YC
Tzeng NS
author_facet Chen LF
Lin CE
Chou YC
Mao WC
Chen YC
Tzeng NS
author_sort Chen LF
title A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
title_short A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
title_full A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
title_fullStr A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
title_full_unstemmed A comparison of complex sleep behaviors with two short-acting Z-hypnosedative drugs in nonpsychotic patients
title_sort comparison of complex sleep behaviors with two short-acting z-hypnosedative drugs in nonpsychotic patients
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/bf2ce716c90b4f7c9e79bde8a4404242
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