An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy

Non-covalent glycosyl donor activation often requires high organocatalyst loadings. Here, the authors demonstrate that strain-release glycosylations can take place at very low thiourea catalyst loadings. In addition, the authors developed a one-pot multicatalytic strategy that can diversify glycosid...

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Main Authors:	Chunfa Xu, Charles C. J. Loh
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/bf2fd9e1731b4649aed90bc2f3e92b75
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spelling	oai:doaj.org-article:bf2fd9e1731b4649aed90bc2f3e92b752021-12-02T15:34:43ZAn ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy10.1038/s41467-018-06329-42041-1723https://doaj.org/article/bf2fd9e1731b4649aed90bc2f3e92b752018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06329-4https://doaj.org/toc/2041-1723Non-covalent glycosyl donor activation often requires high organocatalyst loadings. Here, the authors demonstrate that strain-release glycosylations can take place at very low thiourea catalyst loadings. In addition, the authors developed a one-pot multicatalytic strategy that can diversify glycosides rapidly.Chunfa XuCharles C. J. LohNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chunfa Xu Charles C. J. Loh An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
description	Non-covalent glycosyl donor activation often requires high organocatalyst loadings. Here, the authors demonstrate that strain-release glycosylations can take place at very low thiourea catalyst loadings. In addition, the authors developed a one-pot multicatalytic strategy that can diversify glycosides rapidly.
format	article
author	Chunfa Xu Charles C. J. Loh
author_facet	Chunfa Xu Charles C. J. Loh
author_sort	Chunfa Xu
title	An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
title_short	An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
title_full	An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
title_fullStr	An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
title_full_unstemmed	An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
title_sort	ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bf2fd9e1731b4649aed90bc2f3e92b75
work_keys_str_mv	AT chunfaxu anultralowthioureacatalyzedstrainreleaseglycosylationandamulticatalyticdiversificationstrategy AT charlescjloh anultralowthioureacatalyzedstrainreleaseglycosylationandamulticatalyticdiversificationstrategy AT chunfaxu ultralowthioureacatalyzedstrainreleaseglycosylationandamulticatalyticdiversificationstrategy AT charlescjloh ultralowthioureacatalyzedstrainreleaseglycosylationandamulticatalyticdiversificationstrategy
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An ultra-low thiourea catalyzed strain-release glycosylation and a multicatalytic diversification strategy

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