Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

ABSTRACT Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface. Here, we demonstrate that the repeating protein subunit pattern common to most virus capsids is a molecular patte...

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Autores principales: Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
pattern recognition
bacterial superinfection
innate immunity
Toll-like receptors
virology
virus-host interactions
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bf3aeed89b554e81bd3b7e859806801e
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