Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107

ABSTRACT Macrophages are a target of human immunodeficiency virus type 1 (HIV-1) and may serve as a viral reservoir during antiretroviral therapy (ART). Their susceptibility to HIV-1 infection is subject to variations from permissiveness to resistance depending on their origin, tissue localization,...

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Autores principales: Robert Lodge, Nicolas Bellini, Mélanie Laporte, Syim Salahuddin, Jean-Pierre Routy, Petronela Ancuta, Cecilia T. Costiniuk, Mohammad-Ali Jenabian, Éric A. Cohen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/bf3c9c672de24376b80f6cc1733e60a9
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