INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module

The Integrator complex (INT) is responsible for the 3′-end processing of several classes of non-coding RNAs. Here the authors show that the INTS10-INTS13-INTS14 complex forms a distinct submodule of INT and suggest it facilitates RNA substrate targeting.

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Autores principales:	Kevin Sabath, Melanie L. Stäubli, Sabrina Marti, Alexander Leitner, Murielle Moes, Stefanie Jonas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bf3f2057cddb4eac81b86a74bf8c4351
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spelling	oai:doaj.org-article:bf3f2057cddb4eac81b86a74bf8c43512021-12-02T18:34:22ZINTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module10.1038/s41467-020-17232-22041-1723https://doaj.org/article/bf3f2057cddb4eac81b86a74bf8c43512020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17232-2https://doaj.org/toc/2041-1723The Integrator complex (INT) is responsible for the 3′-end processing of several classes of non-coding RNAs. Here the authors show that the INTS10-INTS13-INTS14 complex forms a distinct submodule of INT and suggest it facilitates RNA substrate targeting.Kevin SabathMelanie L. StäubliSabrina MartiAlexander LeitnerMurielle MoesStefanie JonasNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kevin Sabath Melanie L. Stäubli Sabrina Marti Alexander Leitner Murielle Moes Stefanie Jonas INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
description	The Integrator complex (INT) is responsible for the 3′-end processing of several classes of non-coding RNAs. Here the authors show that the INTS10-INTS13-INTS14 complex forms a distinct submodule of INT and suggest it facilitates RNA substrate targeting.
format	article
author	Kevin Sabath Melanie L. Stäubli Sabrina Marti Alexander Leitner Murielle Moes Stefanie Jonas
author_facet	Kevin Sabath Melanie L. Stäubli Sabrina Marti Alexander Leitner Murielle Moes Stefanie Jonas
author_sort	Kevin Sabath
title	INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
title_short	INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
title_full	INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
title_fullStr	INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
title_full_unstemmed	INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module
title_sort	ints10–ints13–ints14 form a functional module of integrator that binds nucleic acids and the cleavage module
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bf3f2057cddb4eac81b86a74bf8c4351
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INTS10–INTS13–INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module

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