Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation

Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation

The characterisation of B cell progenitors could benefit from single cell RNA analysis. Here the authors show distinct transcriptional profiles of B cell progenitors which are dependent upon pre-BCR and these profiles can be related to B cell transformation in lymphoblastic leukaemia.

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Detalles Bibliográficos
Autores principales: Robin D. Lee, Sarah A. Munro, Todd P. Knutson, Rebecca S. LaRue, Lynn M. Heltemes-Harris, Michael A. Farrar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/bf459a4d617646fcb5ab701582999f27
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