Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data

Abstract Prescription patterns of antipsychotic drugs (APDs) are typically sourced from country-specific data. In this study, a digital pharmacoepidemiological approach was used to investigate APD preferences globally. Publicly available data on worldwide web search intensities in Google for 19 typi...

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Autor principal: Richard Ågren
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bf4820e5c82943559cf3742555458988
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spelling oai:doaj.org-article:bf4820e5c82943559cf37425554589882021-12-02T16:06:10ZWorldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data10.1038/s41598-021-92204-02045-2322https://doaj.org/article/bf4820e5c82943559cf37425554589882021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92204-0https://doaj.org/toc/2045-2322Abstract Prescription patterns of antipsychotic drugs (APDs) are typically sourced from country-specific data. In this study, a digital pharmacoepidemiological approach was used to investigate APD preferences globally. Publicly available data on worldwide web search intensities in Google for 19 typical and 22 atypical APDs were temporally and spatially normalized and correlated with reported prescription data. The results demonstrated an increasing global preference for atypical over typical APDs since 2007, with quetiapine, olanzapine, risperidone, and aripiprazole showing the largest search intensities in 2020. Cross-sectional analysis of 122 countries in 2020 showed pronounced differences in atypical/typical APD preferences that correlated with gross domestic product per capita. In conclusion, the investigation provides temporal and spatial assessments of global APD preferences and shows a trend towards atypical APDs, although with a relative preference for typical APDs in low-income countries. Similar data-sourcing methodologies allow for prospective studies of other prescription drugs.Richard ÅgrenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Richard Ågren
Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
description Abstract Prescription patterns of antipsychotic drugs (APDs) are typically sourced from country-specific data. In this study, a digital pharmacoepidemiological approach was used to investigate APD preferences globally. Publicly available data on worldwide web search intensities in Google for 19 typical and 22 atypical APDs were temporally and spatially normalized and correlated with reported prescription data. The results demonstrated an increasing global preference for atypical over typical APDs since 2007, with quetiapine, olanzapine, risperidone, and aripiprazole showing the largest search intensities in 2020. Cross-sectional analysis of 122 countries in 2020 showed pronounced differences in atypical/typical APD preferences that correlated with gross domestic product per capita. In conclusion, the investigation provides temporal and spatial assessments of global APD preferences and shows a trend towards atypical APDs, although with a relative preference for typical APDs in low-income countries. Similar data-sourcing methodologies allow for prospective studies of other prescription drugs.
format article
author Richard Ågren
author_facet Richard Ågren
author_sort Richard Ågren
title Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
title_short Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
title_full Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
title_fullStr Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
title_full_unstemmed Worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on Google Trends data
title_sort worldwide antipsychotic drug search intensities: pharmacoepidemological estimations based on google trends data
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bf4820e5c82943559cf3742555458988
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