Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex

Objectives. Despite extensive research efforts, mechanisms participating on development of Alzheimer’s disease (AD) are covered only partially. Data from the last decades indicate that various stressors, as etiological factors, may play a role of in the AD. Therefore, we investigated the effect of t...

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Autores principales:	Padova Alexandra, Rokytova Ivana, Mravec Boris, Kvetnansky Richard, Vargovic Peter
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	acute stress amyloid precursor protein immobilization lipopolysaccharide neuroinflammation Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/bf4ef59b0c5d49b18d481e35aa56d556
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spelling	oai:doaj.org-article:bf4ef59b0c5d49b18d481e35aa56d5562021-12-02T17:49:32ZExposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex1336-032910.2478/enr-2019-0012https://doaj.org/article/bf4ef59b0c5d49b18d481e35aa56d5562019-04-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0012https://doaj.org/toc/1336-0329Objectives. Despite extensive research efforts, mechanisms participating on development of Alzheimer’s disease (AD) are covered only partially. Data from the last decades indicate that various stressors, as etiological factors, may play a role of in the AD. Therefore, we investigated the effect of two acute stressors, immobilization (IMO) and lipopolysaccharide (LPS), on the AD-related neuropathology.Padova AlexandraRokytova IvanaMravec BorisKvetnansky RichardVargovic PeterSciendoarticleacute stressamyloid precursor proteinimmobilizationlipopolysaccharideneuroinflammationDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 2, Pp 100-109 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute stress amyloid precursor protein immobilization lipopolysaccharide neuroinflammation Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	acute stress amyloid precursor protein immobilization lipopolysaccharide neuroinflammation Diseases of the endocrine glands. Clinical endocrinology RC648-665 Padova Alexandra Rokytova Ivana Mravec Boris Kvetnansky Richard Vargovic Peter Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
description	Objectives. Despite extensive research efforts, mechanisms participating on development of Alzheimer’s disease (AD) are covered only partially. Data from the last decades indicate that various stressors, as etiological factors, may play a role of in the AD. Therefore, we investigated the effect of two acute stressors, immobilization (IMO) and lipopolysaccharide (LPS), on the AD-related neuropathology.
format	article
author	Padova Alexandra Rokytova Ivana Mravec Boris Kvetnansky Richard Vargovic Peter
author_facet	Padova Alexandra Rokytova Ivana Mravec Boris Kvetnansky Richard Vargovic Peter
author_sort	Padova Alexandra
title	Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
title_short	Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
title_full	Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
title_fullStr	Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
title_full_unstemmed	Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex
title_sort	exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of alzheimer’s disease in the mice brain cortex
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/bf4ef59b0c5d49b18d481e35aa56d556
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Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex

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