The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding

The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding

The folding of outer membrane proteins (OMPs) is catalyzed by the βbarrel assembly machinery (BAM). Here, structural and functional analyses of BAM stabilized in distinct conformations elucidate the roles of lateral gate opening and interactions of BAM with the lipid bilayer in OMP assembly.

Saved in:
Bibliographic Details
Main Authors: Paul White, Samuel F. Haysom, Matthew G. Iadanza, Anna J. Higgins, Jonathan M. Machin, James M. Whitehouse, Jim E. Horne, Bob Schiffrin, Charlotte Carpenter-Platt, Antonio N. Calabrese, Kelly M. Storek, Steven T. Rutherford, David J. Brockwell, Neil A. Ranson, Sheena E. Radford
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/bf4f9d65548640299d6a3b164c8b8b9d
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/bf4f9d65548640299d6a3b164c8b8b9d

Similar Items