Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects

Background: Increased C-reactive protein (CRP) levels are associated with various diseases such as cardiovascular diseases (CVDs), periodontal diseases, and other inflammatory diseases and can be an effective biomarker for predicting future risks of periodontal diseases. Aims: The present trial was...

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Autores principales:	Wagisha Barbi, Saurav Kumar, Sonal Sinha, Mehdi Askari, Swati Priya, Shubham J Kumar
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	cardiovascular diseases c-reactive protein inflammatory diseases obesity periodontal diseases Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/bf5c0eaa2d3c4e239857783f41293625
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spelling	oai:doaj.org-article:bf5c0eaa2d3c4e239857783f412936252021-11-19T12:15:53ZReliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects0975-740610.4103/jpbs.jpbs_251_21https://doaj.org/article/bf5c0eaa2d3c4e239857783f412936252021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1458;epage=1461;aulast=Barbihttps://doaj.org/toc/0975-7406Background: Increased C-reactive protein (CRP) levels are associated with various diseases such as cardiovascular diseases (CVDs), periodontal diseases, and other inflammatory diseases and can be an effective biomarker for predicting future risks of periodontal diseases. Aims: The present trial was carried out to evaluate if CRP levels are lower in healthy and young individuals as compared to individuals with high body mass index (BMI), gingival index, and CVDs by assessing CRP levels in young and old individuals (more than 45 years). Materials and Methods: A total of 174 participants were recruited for the study and were divided into three following groups: Less than 45 years healthy participants (n = 124), more than 45 years healthy participants, and more 45-year-old participants with CVDs (n = 25). The collected data were subjected to the statistical analysis. Results: In Group I, females had a CRP level of 8476 ± 6.86 pg, females of Group II had a CRP value of 13,262 ± 3.76, and in females of Group III CRP value was 22,761 ± 6.24 pg. These values, respectively, for males were 8494 ± 7.68, 13,840 ± 4.82, and 13,839 ± 3.8. In smokers, the CRP values for Group I, II, and III were 29,012 ± 14.66, 12,568 ± 4.16, and 16,826 ± 3.42, respectively. Conclusion: CRP levels were higher in males as compared to females. Higher BMI was associated with higher values of CRP. The participants with higher BMI presented higher CRP values irrespective of age.Wagisha BarbiSaurav KumarSonal SinhaMehdi AskariSwati PriyaShubham J KumarWolters Kluwer Medknow Publicationsarticlecardiovascular diseasesc-reactive proteininflammatory diseasesobesityperiodontal diseasesPharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1458-1461 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiovascular diseases c-reactive protein inflammatory diseases obesity periodontal diseases Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
spellingShingle	cardiovascular diseases c-reactive protein inflammatory diseases obesity periodontal diseases Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 Wagisha Barbi Saurav Kumar Sonal Sinha Mehdi Askari Swati Priya Shubham J Kumar Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
description	Background: Increased C-reactive protein (CRP) levels are associated with various diseases such as cardiovascular diseases (CVDs), periodontal diseases, and other inflammatory diseases and can be an effective biomarker for predicting future risks of periodontal diseases. Aims: The present trial was carried out to evaluate if CRP levels are lower in healthy and young individuals as compared to individuals with high body mass index (BMI), gingival index, and CVDs by assessing CRP levels in young and old individuals (more than 45 years). Materials and Methods: A total of 174 participants were recruited for the study and were divided into three following groups: Less than 45 years healthy participants (n = 124), more than 45 years healthy participants, and more 45-year-old participants with CVDs (n = 25). The collected data were subjected to the statistical analysis. Results: In Group I, females had a CRP level of 8476 ± 6.86 pg, females of Group II had a CRP value of 13,262 ± 3.76, and in females of Group III CRP value was 22,761 ± 6.24 pg. These values, respectively, for males were 8494 ± 7.68, 13,840 ± 4.82, and 13,839 ± 3.8. In smokers, the CRP values for Group I, II, and III were 29,012 ± 14.66, 12,568 ± 4.16, and 16,826 ± 3.42, respectively. Conclusion: CRP levels were higher in males as compared to females. Higher BMI was associated with higher values of CRP. The participants with higher BMI presented higher CRP values irrespective of age.
format	article
author	Wagisha Barbi Saurav Kumar Sonal Sinha Mehdi Askari Swati Priya Shubham J Kumar
author_facet	Wagisha Barbi Saurav Kumar Sonal Sinha Mehdi Askari Swati Priya Shubham J Kumar
author_sort	Wagisha Barbi
title	Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
title_short	Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
title_full	Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
title_fullStr	Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
title_full_unstemmed	Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
title_sort	reliability of c-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/bf5c0eaa2d3c4e239857783f41293625
work_keys_str_mv	AT wagishabarbi reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects AT sauravkumar reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects AT sonalsinha reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects AT mehdiaskari reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects AT swatipriya reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects AT shubhamjkumar reliabilityofcreactiveproteinasabiomarkerforcardiovascularandoraldiseasesinyoungandoldsubjects
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Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects

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