Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats.

Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats.

PCB 180 is a persistent non-dioxin-like polychlorinated biphenyl (NDL-PCB) abundantly present in food and the environment. Risk characterization of NDL-PCBs is confounded by the presence of highly potent dioxin-like impurities. We used ultrapure PCB 180 to characterize its toxicity profile in a 28-d...

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Auteurs principaux: Matti Viluksela, Päivi Heikkinen, Leo T M van der Ven, Filip Rendel, Robert Roos, Javier Esteban, Merja Korkalainen, Sanna Lensu, Hanna M Miettinen, Kari Savolainen, Satu Sankari, Hellmuth Lilienthal, Annika Adamsson, Jorma Toppari, Maria Herlin, Mikko Finnilä, Juha Tuukkanen, Heather A Leslie, Timo Hamers, Gerd Hamscher, Lauy Al-Anati, Ulla Stenius, Kine-Susann Dervola, Inger-Lise Bogen, Frode Fonnum, Patrik L Andersson, Dieter Schrenk, Krister Halldin, Helen Håkansson
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/bf5d98a2a2714b9eac8e5ee07feeb4f4
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