Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis
Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast c...
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| Autores principales: | , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/bf5f51d3ae774ad78c6e50dc269ae7a4 |
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| Sumario: | Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast cancer subtypes. |
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