Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis
Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast c...
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Nature Portfolio
2021
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oai:doaj.org-article:bf5f51d3ae774ad78c6e50dc269ae7a42021-12-02T17:51:20ZMammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis10.1038/s42003-021-02201-22399-3642https://doaj.org/article/bf5f51d3ae774ad78c6e50dc269ae7a42021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02201-2https://doaj.org/toc/2399-3642Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast cancer subtypes.Kohei SaekiGregory ChangNoriko KanayaXiwei WuJinhui WangLauren BernalDesiree HaSusan L. NeuhausenShiuan ChenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021) |
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DOAJ |
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DOAJ |
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EN |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Kohei Saeki Gregory Chang Noriko Kanaya Xiwei Wu Jinhui Wang Lauren Bernal Desiree Ha Susan L. Neuhausen Shiuan Chen Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
description |
Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast cancer subtypes. |
format |
article |
author |
Kohei Saeki Gregory Chang Noriko Kanaya Xiwei Wu Jinhui Wang Lauren Bernal Desiree Ha Susan L. Neuhausen Shiuan Chen |
author_facet |
Kohei Saeki Gregory Chang Noriko Kanaya Xiwei Wu Jinhui Wang Lauren Bernal Desiree Ha Susan L. Neuhausen Shiuan Chen |
author_sort |
Kohei Saeki |
title |
Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
title_short |
Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
title_full |
Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
title_fullStr |
Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
title_full_unstemmed |
Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
title_sort |
mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bf5f51d3ae774ad78c6e50dc269ae7a4 |
work_keys_str_mv |
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1718379310725726208 |