Charting organellar importomes by quantitative mass spectrometry

Knowing the specific protein content of individual organelles is necessary for an integrated understanding of cellular physiology. Here the authors describe a mass spectrometry-based approach to identify the substrates of distinct protein import pathways and define organellar proteomes.

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Detalles Bibliográficos
Autores principales: Christian D. Peikert, Jan Mani, Marcel Morgenstern, Sandro Käser, Bettina Knapp, Christoph Wenger, Anke Harsman, Silke Oeljeklaus, André Schneider, Bettina Warscheid
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Q
Acceso en línea:https://doaj.org/article/bf7073abf7dd409ea6d6cecc74034615
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Descripción
Sumario:Knowing the specific protein content of individual organelles is necessary for an integrated understanding of cellular physiology. Here the authors describe a mass spectrometry-based approach to identify the substrates of distinct protein import pathways and define organellar proteomes.