On clinical trial fragility due to patients lost to follow up

Abstract Background Clinical trials routinely have patients lost to follow up. We propose a methodology to understand their possible effect on the results of statistical tests by altering the concept of the fragility index to treat the outcomes of observed patients as fixed but incorporate the poten...

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Bibliographic Details
Main Authors: Benjamin R. Baer, Stephen E. Fremes, Mario Gaudino, Mary Charlson, Martin T. Wells
Format: article
Language:EN
Published: BMC 2021
Subjects:
Online Access:https://doaj.org/article/bf76edffb4524432be3b3cc45054d90e
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