Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes

Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes

Ty3 retrotransposon integrates with an exquisite specificity upstream of RNA Polymerase III-transcribed genes, such as transfer RNAs. Here the authors resolve a cryo-EM structure of an active Ty3 intasome in complex with a TFIIIB-bound tRNA promoter, shedding light into the molecular determinants of...

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Autores principales: Guillermo Abascal-Palacios, Laura Jochem, Carlos Pla-Prats, Fabienne Beuron, Alessandro Vannini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/bf7b6a981a694ea8b4a21cd408b7a073
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