Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells

Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells

Abstract Ischemia is a major cause of kidney damage. Proximal tubular epithelial cells (PTECs) are highly susceptible to ischemic insults that frequently cause acute kidney injury (AKI), a potentially life-threatening condition with high mortality. Accumulating evidence has identified altered mitoch...

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Autores principales: Timo N. Haschler, Harry Horsley, Monika Balys, Glenn Anderson, Jan-Willem Taanman, Robert J. Unwin, Jill T. Norman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bf7c614184604ba8a7792b2421c0cbc7
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