Mutational processes in cancer preferentially affect binding of particular transcription factors

Mutational processes in cancer preferentially affect binding of particular transcription factors

Abstract Protein binding microarrays provide comprehensive information about the DNA binding specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of DNA sequence variation on TF binding. There has also been substantial progress in dissecting the pattern...

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Autores principales: Mo Liu, Arnoud Boot, Alvin W. T. Ng, Raluca Gordân, Steven G. Rozen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/bf8428da735448df9592fa79a3a34db2
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