Mutational processes in cancer preferentially affect binding of particular transcription factors
Abstract Protein binding microarrays provide comprehensive information about the DNA binding specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of DNA sequence variation on TF binding. There has also been substantial progress in dissecting the pattern...
Saved in:
Main Authors: | Mo Liu, Arnoud Boot, Alvin W. T. Ng, Raluca Gordân, Steven G. Rozen |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/bf8428da735448df9592fa79a3a34db2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mutations in an AP2 transcription factor-like gene affect internode length and leaf shape in maize.
by: Fukun Jiang, et al.
Published: (2012) -
Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1
by: Francesca Pasutto, et al.
Published: (2017) -
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
by: Mitchell J. Machiela, et al.
Published: (2016) -
Mutational signatures in GATA3 transcription factor and its DNA binding domain that stimulate breast cancer and HDR syndrome
by: Atlal El-Assaad, et al.
Published: (2021) -
The Sox2 transcription factor binds RNA
by: Zachariah E. Holmes, et al.
Published: (2020)