Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

M1 and M2 cells are representative of proinflammatory versus resolving macrophages, respectively. Here the authors characterize the lipid mediator response to bacterial infection by these cells and show that differing panels of leukotrienes and specialized pro-resolving mediators contribute to contr...

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Autores principales:	Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C. Norris, Nan Chiang, Charles N. Serhan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bf8ddff4771343aba2fa655e1c5cf782
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spelling	oai:doaj.org-article:bf8ddff4771343aba2fa655e1c5cf7822021-12-02T17:31:44ZHuman macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity10.1038/s41467-017-02538-52041-1723https://doaj.org/article/bf8ddff4771343aba2fa655e1c5cf7822018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02538-5https://doaj.org/toc/2041-1723M1 and M2 cells are representative of proinflammatory versus resolving macrophages, respectively. Here the authors characterize the lipid mediator response to bacterial infection by these cells and show that differing panels of leukotrienes and specialized pro-resolving mediators contribute to control of the dichotomy.Oliver WerzJana GerstmeierStephania LibrerosXavier De la RosaMarkus WernerPaul C. NorrisNan ChiangCharles N. SerhanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Oliver Werz Jana Gerstmeier Stephania Libreros Xavier De la Rosa Markus Werner Paul C. Norris Nan Chiang Charles N. Serhan Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
description	M1 and M2 cells are representative of proinflammatory versus resolving macrophages, respectively. Here the authors characterize the lipid mediator response to bacterial infection by these cells and show that differing panels of leukotrienes and specialized pro-resolving mediators contribute to control of the dichotomy.
format	article
author	Oliver Werz Jana Gerstmeier Stephania Libreros Xavier De la Rosa Markus Werner Paul C. Norris Nan Chiang Charles N. Serhan
author_facet	Oliver Werz Jana Gerstmeier Stephania Libreros Xavier De la Rosa Markus Werner Paul C. Norris Nan Chiang Charles N. Serhan
author_sort	Oliver Werz
title	Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
title_short	Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
title_full	Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
title_fullStr	Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
title_full_unstemmed	Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
title_sort	human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bf8ddff4771343aba2fa655e1c5cf782
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Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

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