The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype

Chromosomal translocations involving the nucleoporin <i>NUP98</i> gene are recurrently identified in leukemia; yet, the cellular defects accompanying NUP98 fusion proteins are poorly characterized. NUP98 fusions cause changes in nuclear and nuclear envelope (NE) organization, in particul...

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Bibliographic Details
Main Authors: Marcela Vaz, Birthe Fahrenkrog
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
PcG
Online Access:https://doaj.org/article/bf8ef75798a148e086d06304af3e71d3
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