Turnover of Variant Surface Glycoprotein in <named-content content-type="genus-species">Trypanosoma brucei</named-content> Is a Bimodal Process

ABSTRACT African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous GPI-specific phospholipase C (GPI-PLC). However, GPI-PLC is topolo...

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Autores principales:	Paige Garrison, Umaer Khan, Michael Cipriano, Peter J. Bush, Jacquelyn McDonald, Aakash Sur, Peter J. Myler, Terry K. Smith, Stephen L. Hajduk, James D. Bangs
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	trypanosome variant surface glycoprotein glycosylphosphatidylinositol glycosylphosphatidylinositol-specific phospholipase C extracellular vesicles Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/bf9bd0020fb4404db69135c5e3a5c6f5
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Turnover of Variant Surface Glycoprotein in <named-content content-type="genus-species">Trypanosoma brucei</named-content> Is a Bimodal Process

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