Local microRNA delivery targets Palladin and prevents metastatic breast cancer

MicroRNAs represent potential therapeutic targets to control metastasis progression. Here the authors show that miR-96 and miR-182 regulate invasion via Palladin and demonstrate that local delivery of miR-96 and miR-182 may serve as a potential anti-metastatic drug in breast cancer.

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Autores principales: Avital Gilam, João Conde, Daphna Weissglas-Volkov, Nuria Oliva, Eitan Friedman, Natalie Artzi, Noam Shomron
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/bf9f3f38026c4b789a1263ceb549a4eb
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spelling oai:doaj.org-article:bf9f3f38026c4b789a1263ceb549a4eb2021-12-02T14:40:16ZLocal microRNA delivery targets Palladin and prevents metastatic breast cancer10.1038/ncomms128682041-1723https://doaj.org/article/bf9f3f38026c4b789a1263ceb549a4eb2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12868https://doaj.org/toc/2041-1723MicroRNAs represent potential therapeutic targets to control metastasis progression. Here the authors show that miR-96 and miR-182 regulate invasion via Palladin and demonstrate that local delivery of miR-96 and miR-182 may serve as a potential anti-metastatic drug in breast cancer.Avital GilamJoão CondeDaphna Weissglas-VolkovNuria OlivaEitan FriedmanNatalie ArtziNoam ShomronNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Avital Gilam
João Conde
Daphna Weissglas-Volkov
Nuria Oliva
Eitan Friedman
Natalie Artzi
Noam Shomron
Local microRNA delivery targets Palladin and prevents metastatic breast cancer
description MicroRNAs represent potential therapeutic targets to control metastasis progression. Here the authors show that miR-96 and miR-182 regulate invasion via Palladin and demonstrate that local delivery of miR-96 and miR-182 may serve as a potential anti-metastatic drug in breast cancer.
format article
author Avital Gilam
João Conde
Daphna Weissglas-Volkov
Nuria Oliva
Eitan Friedman
Natalie Artzi
Noam Shomron
author_facet Avital Gilam
João Conde
Daphna Weissglas-Volkov
Nuria Oliva
Eitan Friedman
Natalie Artzi
Noam Shomron
author_sort Avital Gilam
title Local microRNA delivery targets Palladin and prevents metastatic breast cancer
title_short Local microRNA delivery targets Palladin and prevents metastatic breast cancer
title_full Local microRNA delivery targets Palladin and prevents metastatic breast cancer
title_fullStr Local microRNA delivery targets Palladin and prevents metastatic breast cancer
title_full_unstemmed Local microRNA delivery targets Palladin and prevents metastatic breast cancer
title_sort local microrna delivery targets palladin and prevents metastatic breast cancer
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/bf9f3f38026c4b789a1263ceb549a4eb
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AT nuriaoliva localmicrornadeliverytargetspalladinandpreventsmetastaticbreastcancer
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