DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD

Objective: To determine the diagnostic accuracy of contrast enhanced computed tomography (CECT) scan in detecting renal cell carcinoma taking histopathology as gold standard. Study Design: Validity Study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Ins...

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Autores principales:	Ayesha Munir, Shahla Zameer, Umairah Kalim
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	computed tomography renal cell carcinoma sensitivity Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bf9f76d63da8465f8a33db010f2a4c67
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spelling	oai:doaj.org-article:bf9f76d63da8465f8a33db010f2a4c672021-11-12T04:12:32ZDIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD0030-96482411-8842https://doaj.org/article/bf9f76d63da8465f8a33db010f2a4c672019-06-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3047/2279https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the diagnostic accuracy of contrast enhanced computed tomography (CECT) scan in detecting renal cell carcinoma taking histopathology as gold standard. Study Design: Validity Study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Institute of Medical Sciences, and Islamabad, from Aug 2017 to Mar 2018. Material and Methods: The study was done on 60 patients with renal masses on ultrasonography. Pregnant females and patients not willing for surgery were excluded. All the subjects underwent pre-contrast and contrastenhanced CT scanning of the abdomen using a multi-sectional spiral CT device. All CT scan findings were interpreted by one consultant radiologist for presence or absence of renal cell carcinoma. CT scan findings were correlated with histopathological findings. Data was analyzed with SPSS v 20. Results: Mean age at the time of presentation was 56.79 ± 9.25 years. Out of these 60 patients, 41 (68.33%) were males and 19 (31.67%) were females with male to female ratio of 2.2:1. In CT scan positive patients, 34 were true positive and 2 were false positive. Among CT scan negative patients, 4 were false negative (FN) where as 20 were true negative (TN) (p=0.0001). Overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of contrast enhanced computed tomography (CT) in detecting renal cell carcinoma patients was 89.47%, 90.91%, 94.44%, 83.33% and 90.0% respectively. Conclusion: This study concluded that CECT scan is a highly sensitive and accurate non-invasive modality for detecting renal cell carcinoma. DownloadsAyesha MunirShahla ZameerUmairah KalimArmy Medical College Rawalpindiarticlecomputed tomographyrenal cell carcinomasensitivityMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 3, Pp 644-647 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	computed tomography renal cell carcinoma sensitivity Medicine R Medicine (General) R5-920
spellingShingle	computed tomography renal cell carcinoma sensitivity Medicine R Medicine (General) R5-920 Ayesha Munir Shahla Zameer Umairah Kalim DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
description	Objective: To determine the diagnostic accuracy of contrast enhanced computed tomography (CECT) scan in detecting renal cell carcinoma taking histopathology as gold standard. Study Design: Validity Study. Place and Duration of Study: Study was conducted in Department of Radiology, Pakistan Institute of Medical Sciences, and Islamabad, from Aug 2017 to Mar 2018. Material and Methods: The study was done on 60 patients with renal masses on ultrasonography. Pregnant females and patients not willing for surgery were excluded. All the subjects underwent pre-contrast and contrastenhanced CT scanning of the abdomen using a multi-sectional spiral CT device. All CT scan findings were interpreted by one consultant radiologist for presence or absence of renal cell carcinoma. CT scan findings were correlated with histopathological findings. Data was analyzed with SPSS v 20. Results: Mean age at the time of presentation was 56.79 ± 9.25 years. Out of these 60 patients, 41 (68.33%) were males and 19 (31.67%) were females with male to female ratio of 2.2:1. In CT scan positive patients, 34 were true positive and 2 were false positive. Among CT scan negative patients, 4 were false negative (FN) where as 20 were true negative (TN) (p=0.0001). Overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of contrast enhanced computed tomography (CT) in detecting renal cell carcinoma patients was 89.47%, 90.91%, 94.44%, 83.33% and 90.0% respectively. Conclusion: This study concluded that CECT scan is a highly sensitive and accurate non-invasive modality for detecting renal cell carcinoma. Downloads
format	article
author	Ayesha Munir Shahla Zameer Umairah Kalim
author_facet	Ayesha Munir Shahla Zameer Umairah Kalim
author_sort	Ayesha Munir
title	DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
title_short	DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
title_full	DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
title_fullStr	DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
title_full_unstemmed	DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD
title_sort	diagnostic accuracy of contrast enhanced computed tomography in diagnosing renal cell carcinoma, taking histopathology as gold standard
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/bf9f76d63da8465f8a33db010f2a4c67
work_keys_str_mv	AT ayeshamunir diagnosticaccuracyofcontrastenhancedcomputedtomographyindiagnosingrenalcellcarcinomatakinghistopathologyasgoldstandard AT shahlazameer diagnosticaccuracyofcontrastenhancedcomputedtomographyindiagnosingrenalcellcarcinomatakinghistopathologyasgoldstandard AT umairahkalim diagnosticaccuracyofcontrastenhancedcomputedtomographyindiagnosingrenalcellcarcinomatakinghistopathologyasgoldstandard
_version_	1718431313817501696

DIAGNOSTIC ACCURACY OF CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN DIAGNOSING RENAL CELL CARCINOMA, TAKING HISTOPATHOLOGY AS GOLD STANDARD

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