Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors

Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PB...

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Autores principales: Tomohiko Matsuo, Tomoko Isosaka, Lijun Tang, Tomoyoshi Soga, Reiko Kobayakawa, Ko Kobayakawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a
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spelling oai:doaj.org-article:bfa63aa7e10d4f18858074c827e1d90a2021-12-02T11:50:30ZArtificial hibernation/life-protective state induced by thiazoline-related innate fear odors10.1038/s42003-020-01629-22399-3642https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01629-2https://doaj.org/toc/2399-3642Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilitiesTomohiko MatsuoTomoko IsosakaLijun TangTomoyoshi SogaReiko KobayakawaKo KobayakawaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Tomohiko Matsuo
Tomoko Isosaka
Lijun Tang
Tomoyoshi Soga
Reiko Kobayakawa
Ko Kobayakawa
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
description Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilities
format article
author Tomohiko Matsuo
Tomoko Isosaka
Lijun Tang
Tomoyoshi Soga
Reiko Kobayakawa
Ko Kobayakawa
author_facet Tomohiko Matsuo
Tomoko Isosaka
Lijun Tang
Tomoyoshi Soga
Reiko Kobayakawa
Ko Kobayakawa
author_sort Tomohiko Matsuo
title Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_short Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_full Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_fullStr Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_full_unstemmed Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
title_sort artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a
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