Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors
Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PB...
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Nature Portfolio
2021
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oai:doaj.org-article:bfa63aa7e10d4f18858074c827e1d90a2021-12-02T11:50:30ZArtificial hibernation/life-protective state induced by thiazoline-related innate fear odors10.1038/s42003-020-01629-22399-3642https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01629-2https://doaj.org/toc/2399-3642Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilitiesTomohiko MatsuoTomoko IsosakaLijun TangTomoyoshi SogaReiko KobayakawaKo KobayakawaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
description |
Matsuo, Isosaka, et al report that innate fear, but not learned fear, in mice results in systemic hypothermia/hypometabolism and suppressed aerobic metabolism, which enables survival in hypoxic environments. They demonstrate that this process is orchestrated via the brain stem Sp5/NST to midbrain PBN pathway. This study provides insight into the relationship between innate fear and its intrinsic life protective abilities |
format |
article |
author |
Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa |
author_facet |
Tomohiko Matsuo Tomoko Isosaka Lijun Tang Tomoyoshi Soga Reiko Kobayakawa Ko Kobayakawa |
author_sort |
Tomohiko Matsuo |
title |
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
title_short |
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
title_full |
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
title_fullStr |
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
title_full_unstemmed |
Artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
title_sort |
artificial hibernation/life-protective state induced by thiazoline-related innate fear odors |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bfa63aa7e10d4f18858074c827e1d90a |
work_keys_str_mv |
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1718395188465893376 |